Stabilization of the Amorphous Structure of Spray-Dried Drug Nanoparticles
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A kinetic model for solid-state polycondensation of nylon-6 was developed by extrapolation of the melt chemistry to the amorphous phase of the solid polymer. In this way, a phenomenological description of the process was obtained that required examining al ...
Carrier-mediated drug delivery has emerged as a powerful methodology for the treatment of various pathologies. The therapeutic index of traditional and novel drugs is enhanced via the increase of specificity due to targeting of drugs to a particular tissue ...
While the rheology of non-Brownian suspensions in the dilute regime is well understood, their behavior in the dense limit remains mystifying. As the packing fraction of particles increases, particle motion becomes more collective, leading to a growing leng ...
The functionalization of nanoparticles is conditio sine qua non in studies of specific interaction with a biological target. Often, their biological functionality is achieved by covalent binding of bioactive molecules on a preexisting single surface coatin ...
An enhanced optical absorption, compared to crystalline silicon, was observed in the above gap region together with very low defect-connected absorption in microcrystalline silicon (μc-Si:H) prepared by very high frequency glow discharge technique at 70 MH ...
By addition of Si to a binary transition metal nitride MN (e.g. TiN, ZrN, NbN, CrN), the hardness, thermal stability and chemical inertness of films have been considerably improved. The formation of a ternary M–Si–N ternary phase is possible under specific ...
Tungsten-iron alloy was produced by electrodeposition. The electrodeposited alloy (15 at.% W) possesses a two-phase composite microstructure, containing a nanocrystalline phase of distorted BCC structure with a grain size between 50 to 150 nm and an amorph ...
Recent developments in Raman spectroscopy at high pressure, high temperature and combined high pressure and variable temperature are presented. The instrumental and technical aspects of Raman spectroscopy, and coupling of diamond anvil cells and miniature ...
We study the state of a nanometric helium bubble in bcc-iron as a function of temperature and He content using atomistic calculations. It appears that up to moderate temperatures the Fe lattice can confine He to solid state, in good agreement with known sol ...
Pressure-induced amorphous-phase transitions (amorphization) have been observed in framework silicates like quartz and feldspars. A similar crystalline to highly disordered solid phase transition is reported in this study for two zeolites, scolecite and me ...