Publication
In-Vivo Validation of Fully Implantable Multi-Panel Devices for Remote Monitoring of Metabolism
Publications associées (32)
Associations between in vitro, in vivo and in silico cell classes in mouse primary visual cortex
Werner Alfons Hilda Van Geit, Anatoly Buchin
The brain consists of many cell classes yet in vivo electrophysiology recordings are typically unable to identify and monitor their activity in the behaving animal. Here, we employed a systematic approach to link cellular, multi-modal in vitro properties f ...
2023In vivo and ex vivo range of motion in the fire salamander Salamandra salamandra
Joint range of motion (RoM) analyses are fundamental to our understanding of how an animal moves throughout its ecosystem. Recent technological advances allow for more detailed quantification of this RoM (e.g. including interaction of degrees of freedom) b ...
2022In vitro and in vivo NIR fluorescence lifetime imaging with a time-gated SPAD camera
Edoardo Charbon, Claudio Bruschini, Arin Can Ülkü
Near-infrared (NIR) fluorescence lifetime imaging (FLI) provides a unique contrast mechanism to monitor biological parameters and molecular events in vivo. Single-photon avalanche diode (SPAD) cameras have been recently demonstrated in FLI microscopy (FLIM ...
Optica Publishing Group2022Visualization, Interactive Handling and Simulation of Molecules in Commodity Augmented Reality in Web Browsers Using moleculARweb's Virtual Modeling Kits
Matteo Dal Peraro, Luciano Andres Abriata, Lucien Fabrice Krapp, Fabio Jose Cortes Rodriguez
moleculARweb (https://molecularweb.epfl.ch) began as a website for education and outreach in chemistry and structural biology through augmented reality (AR) content that runs in the web browsers of regular devices like smartphones, tablets, and computers. ...
SWISS CHEMICAL SOC2022Organoids as tools for fundamental discovery and translation-A Keystone Symposia report
Complex three-dimensional in vitro organ-like models, or organoids, offer a unique biological tool with distinct advantages over two-dimensional cell culture systems, which can be too simplistic, and animal models, which can be too complex and may fail to ...
WILEY2022Insights gained from a comprehensive all-against-all transcription factor binding motif benchmarking study
Giovanna Ambrosini, Philipp Bucher, Romain Fernand Pietro Groux
BackgroundPositional weight matrix (PWM) is a de facto standard model to describe transcription factor (TF) DNA binding specificities. PWMs inferred from in vivo or in vitro data are stored in many databases and used in a plethora of biological application ...
2020Rapid evaluation of bioactive Ti-based surfaces using an in vitro titration method
Paul Bowen, Jacques Lemaître, Weitian Zhao
The prediction of implant behavior in vivo by the use of easy-to-perform in vitro methods is of great interest in biomaterials research. Simulated body fluids (SBFs) have been proposed and widely used to evaluate the bone-bonding ability of implant materia ...
Springer2019Innovative Tools and in vivo Methods for Tuberculosis Drug Discovery and Development
Worldwide, tuberculosis (TB) is the leading cause of death due to a single infectious agent, claiming 1.6 million human lives and causing >10 million new cases in 2017 alone, mostly in low-income regions. The intracellular pathogen Mycobacterium tuberculos ...
EPFL2019An ecotoxicological view on neurotoxicity assessment
The numbers of potential neurotoxicants in the environment are raising and pose a great risk for humans and the environment. Currently neurotoxicity assessment is mostly performed to predict and prevent harm to human populations. Despite all the efforts in ...
SPRINGEROPEN2018Calcium phosphate formation on titanium-based surfaces: bioactivity evaluated by in vitro methods
The prediction of implant behaviors in vivo by the use of easy-to-perform in vitro methods is of great interest in biomaterials research. In the field of bone implants, it is commonly accepted that a spontaneous formation of a hydroxyapatite (HA) layer on ...
EPFL2018