Micro- and nanoscale hierarchical structure of core-shell protein microgels
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We present a novel optofluidic differential method for carrying out absorbance spectroscopy of subnanolitre volumes of liquid samples on a microfluidic chip. Due to the reduction of liquid volume, the absorbance detection in microfluidics is often hindered ...
A microfluidic device for protein preconcentration based on the electrokinetic trapping principle is proposed. It comprises a Nafion strip which is simply cut from a commercially available membrane and integrated into a polydimethylsiloxane (PDMS) microflu ...
Since the first compartmentalized neuronal culture described by Robert B. Campenot in 1977, compartmentalized microfluidic devices have been widely used to engineer the cellular environment for cell culture. In previous research by Dr. Anja Kunze, a microf ...
The research areas of tissue engineering and drug development have displayed increased interest in organ-on-a-chip studies, in which physiologically or pathologically relevant tissues can be engineered to test pharmaceutical candidates. Microfluidic techno ...
Extremely sensitive protein detection is crucial for early diagnosis and monitoring of diseases. Present day’s limit of detection for an antibody-antigen recognition-based immunoassay in serum without having to use special target antigen amplification tech ...
Microfluidic structures in poly(dimethylsiloxane) (PDMS) are usually fabricated by optically patterning a resist and subsequently transferring this pattern to PDMS. Such microsystems suffer from reduced resolution, which in turn inhibit the manipulation of ...
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This paper presents the realization of a hydrodynamic microfluidic trap with the goal of sorting MEMS for self-assembly experiments in liquid. A simplified analytical design rule has been compiled and numerically verified. Microfluidic devices have been fa ...
Plasticization of medical grade poly-L-lactide (PLLA) by addition of polyethylene glycol (PEG) with various molar masses has been evaluated as means of producing low stiffness matrices for bioresorbable scaffolds for soft-tissue engineering applications. A ...
Droplet-based microfluidics enables assays to be carried out at very high throughput (up to thousands of samples per second) and enables researchers to work with very limited material, such as primary cells, patient's biopsies or expensive reagents. An add ...
Essential in biomedical research is the necessity of gathering statistically relevant data about large populations of specific biological entities, e.g. organisms, cells or molecules, while preserving detailed information about each single entity under in ...