Application of imaging mass spectrometry approaches to facilitate metal-based anticancer drug research
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Based on the clinical success of platinum-based anti-cancer drugs such as cisplatin, carboplatin and oxaliplatin, a variety of other metal-based anti-cancer compounds are being investigated. In particular, a number of ruthenium-based compounds have been id ...
This paper is intended to stimulate discussion about the creation of a standard for a community participation model of terminology development. It begins with a discussion of why the current state of terminology development in Africa brings forth the need ...
The introductory chapter of the book studies the links between technologies and development, which should first have to address the contribution of modern technologies to sustainable development in all its environmental, social and economic aspects, in ord ...
In our Dalton Transactions Perspective article entitled, 'Metal-based antitumour drugs in the post genomic era', (Dalton Trans., 2006, 1929-1933) we discussed metal-based drugs in light of past decades of research. We concluded that the post-genomic era wo ...
This volume presents an update on the state of research and development in Smoothed Particle Hydrodynamics as it includes all the papers presented at the Third Workshop on SPH at EPFL, the Swiss Federal Institute of Technology in Lausanne, June 4-6, 2008. ...
In this paper we describe Graaasp, a social software currently under development to support the creation of a real usage database of social artifacts. Our goals are twofold: First to offer a generic aggregation service and user interface to people and comm ...
Conventional chemotherapy leads to severe side-effects such as nephrotoxicity, nausea and vomiting and fatigue along with drug resistance. Alkylating agents used to treat cancer were even shown to provoke second cancers, often years after the end of chemot ...
In order to provide an alternative measurement tool for arsenic contamination, we are developing a sensor that uses agarose beads containing a genetically engineered Escherichia coli strain producing a fluorescent signal in response to arsenite. Beads with ...
Nanopharmaceuticals or nanomedicines are defined as nanometer sized (1 to 1000 nm) complex systems, consisting of at least two components, one of which being the biologically active moiety such as a drug, peptide, protein or nucleotide. Several nano-sized ...
Over the last two decades, globalisation has accelerated international migration flows, particularly of skilled labour. Yet, increasing migration by skilled workers from developing countries (“brain drain”) has raised serious concerns internationally about ...