Synaptic patterning and the timescales of cortical dynamics
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The cerebral cortex occupies nearly 80% of the entire volume of the mammalian brain and is thought to subserve higher cognitive functions like memory, attention and sensory perception. The neocortex is the newest part in the evolution of the cerebral corte ...
Sensory information is actively gathered by animals, but the synaptic mechanisms driving neuronal circuit function during active sensory processing are poorly understood. Here, we investigated the synaptically driven membrane potential dynamics during acti ...
Feedback error-related potentials are a promising brain process in the field of rehabilitation since they are related to human learning. Due to the fact that many therapeutic strategies rely on the presentation of feedback stimuli, potentials generated by ...
Integration of multimodal information is essential for the integrative response of the brain and is thought to be accomplished mostly in sensory association areas. However, available evidences in humans and monkeys indicate that this process begins already ...
The aim of this study is to contribute to understand the physiology of the Olfactory System through detailed microcircuit investigation, adopting advanced electrophysiological and anatomical techniques. Multiple patch clamp recordings allow understanding t ...
The short-term plasticity of synaptic transmission between excitatory neurons within a barrel of layer 4 rat somatosensory neocortex was investigated. Action potentials in presynaptic neurons at frequencies ranging from 1 to 100 Hz evoked depressing postsy ...
Changes of synaptic connections between neurons are thought to be the physiological basis of learning. These changes can be gated by neuromodulators that encode the presence of reward. We study a family of reward-modulated synaptic learning rules for spiki ...
The neocortex is the most computationally advanced portion of the brain. It is currently assumed to be composed of a large number of "cortical columns" – intricate arrangements of cortical neurons approximately 300-500 µm in diameter and 2-5 mm in height i ...
The rodent primary somatosensory cortex is spontaneously active in the form of locally synchronous membrane depolarizations (UP states) separated by quiescent hyperpolarized periods (DOWN states) both under anesthesia and during quiet wakefulness. In vivo ...
Small assemblies of Fitzhugh-Nagumo neural oscillators are used to study a type of threshold coupling coming from biology where it is used to model synapses. Phase locking and coincidence detection is modelled in the two most simple coupling configurations ...
