Numerical modeling of hemodynamics scenarios of patient-specific coronary artery bypass grafts
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The mechanical interactions between heart contraction and perfusion of the heart are difficult to study in humans because of the restrictions in inducing changes in hemodynamic and cardiac mechanics parameters during catheterization. We hypothesize that th ...
Coronary artery disease is one of the main causes of death in western countries. The standard of care has become the implantation of a coronary stent, i.e. a small metal-mesh tube reopening the lumen of the artery and maintaining the blood flow to the hear ...
In the cardiovascular system, morphology and functionality are closely related. Altered flow conditions play an important role in the development of arterial disease. In turn, these flow conditions are modified by arterial wall changes. A detailed understa ...
Cardiovascular magnetic resonance has been shown to provide high data quality for myocardial perfusion assessment However, to analyze the perfusion data, some signal processing and modeling is needed to correct for motion related artifacts and limited spat ...
Ieee Service Center, 445 Hoes Lane, Po Box 1331, Piscataway, Nj 08855-1331 Usa2007
Blood flow patterns in the coronary arteries are of interest due to their possible involvement in atherosclerosis localization. Spatial variations in hemodynamic flow patterns are predominantly determined by the vessel geometry. The coronary arteries repre ...
Cardiovascular magnetic resonance has been shown to provide high data quality for myocardial perfusion assessment. However, to analyze the perfusion data, some signal processing and modeling is needed to correct for motion related artifacts and limited spa ...
Drug eluting stents (DES) have been successfully implemented in clinical practice in the treatment against coronary artery disease. Compared to the implantation of bare metal stents, restenosis rates decreased significantly after stenting of DES into coron ...
Materials Research Society, 506 Keystone Drive, Warrendale, Pa 15086-7573 Usa2009
OBJECTIVE: Besides its predictive role in determining cardiovascular risk, C-reactive protein (CRP) may exert direct proatherogenic effects through proinflammatory properties. CRP is mainly produced by hepatocytes in response to interleukin-6 (IL-6) and is ...
In this thesis we propose and analyze the numerical methods for the approximation of axisymmetric flows as well as algorithms suitable for the solution of fluid-structure interaction problems. Our investigation is aimed at, but are not restricted to, the s ...
Aims: Patency failure of small vascular synthetic grafts is still a major problem for coronary and peripheral revascularization. Thus, three new surface coatings of small synthetic grafts were tested in an acute pig model to evaluate their thrombogenicity ...
