Scaffold requirements for periodontal regeneration with enamel matrix derivative proteins
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Synthetic bone substitutes are potentially the future gold standard in orthopaedic and traumatologic surgery. The availability of these bone substitutes with different biomechanical properties may well replace autografts in the future as they overcome comp ...
One of the key problems in dental biomechanics is the prediction of tooth mobility under functional loads. Understanding tooth displacement due to load is becoming more important as new solutions in dental restorations, prosthodontics and orthodontic treat ...
In order to decrease the peri-implant bone loss during the life-time of the implant, oral use of anti-osteoporosis drugs (like bisphosphonates) has been suggested. In this study, bone remodeling parameters identified from clinical trials of alendronate wer ...
Mechanical testing of the periodontal ligament requires a practical experimental model. Bovine teeth are advantageous in terms of size and availability, but information is lacking as to the anatomy and histology of their periodontium. The aim of this study ...
Orthodontic treatments are all based on the experimental evidence that teeth can be forced to move in the dental arch by means of applied mechanical forces. Since it allows for prediction of dental mobility, the mechanical characterization of the tissues i ...
In this thesis, the potential use of fetal bone cells for tissue engineering was evaluated. At first, fetal bone cells were characterized in vitro regarding their proliferation rate, the induction of their osteoblastic phenotype, and their antigenicity. Th ...
Injectable calcium phosphate hydraulic cement (CPHC) is a new bone substitute family. This study aimed to evaluate the use of CPHC in surgical periodontitis-simulating defects in a dog model. CPHC was obtained by adding powder mixtures of different calcium ...
The soft tissue, called periodontal ligament (PDL), that connects the alveolar bone and the tooth root accounts to a large extent for the mobility, stress-distribution and, due to its viscoelastic properties, damping of the bone-tooth complex. The accurate ...
Total Hip Replacement (THR) is today a routine procedure executed more than 800'000 times per year worldwide. THR gives generally satisfactory results, although the quality of outcome is inversely proportional to the age of the patient. In parallel, there ...
Despite total hip replacement (THR) gives generally satisfactory results, the quality of outcome in young patients is markedly decreased compared to the average THR outcome. For this population, pharmacological treatment with bisphosphonate would be benefi ...