Preventing visual function loss in the rd10 mouse model of retinitis pigmentosa using gene editing
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In both scotopic and photopic conditions, the rotation of a grating was found to elicit head movements in mice. The highest spatial frequency eliciting this optomotor response provided an estimate of visual acuity. In male C57BL/6J mice, visual acuity incr ...
Residual micro-saccades, tremor and fixation errors imply that, on different trials in visual tasks, stimulus arrays are inevitably presented at different positions on the retina. Positional variation is likely to be specially important for tasks involving ...
We address the problem of recognizing the visual focus of attention (VFOA) of meeting participants based on their head pose. To this end, the head pose observations are modeled using a Gaussian Mixture Model (GMM) or a Hidden Markov Model (HMM) whose hidde ...
In crowding, neighbouring elements impair the perception of a target. Crowding is often considered a consequence of spatial pooling of visual information. We investigated the role of configural effects in crowding by manipulating the global stimulus config ...
INTRODUCTION: A prominent neurophysiological model of phobia generation holds that specific phobia might result from the uncoupling of unaware subcortical fear responses from aware cortical fear responses. Former responses are thought to be automatic and f ...
Contextual elements can fundamentally change the perception of an embedded target. A recently discovered masking effect, shine-through, allows one to investigate the precise dynamics of contextual modulation of the human visual system. In this shine-throug ...
OBJECTIVE: To explore how baseline lesion composition influenced vision outcomes in patients with age-related macular degeneration (AMD) undergoing photodynamic therapy with verteporfin (Visudyne) for subfoveal choroidal neovascularization (CNV) in the Tre ...
Objective: To evaluate short-term safety and the effects on visual acuity and fluorescein angiography of single or multiple sessions of photodynamic therapy with verteporfin for choroidal neovascularization (CNV) not related to age-related macular degenera ...
OBJECTIVES: To evaluate safety and short-term visual acuity and fluorescein angiographic effects of photodynamic therapy (PDT) after retreatments with verteporfin for choroidal neovascularization (CNV) in age-related macular degeneration (AMD) that demonst ...
Melanin pigments are found in all biological kingdoms. At the cellular level, correct pigmentation depends not only on correct migration of pigment cells (melanocytes) and their precursors (melanoblasts), but also on specialized cytoplasmic organelles, mel ...
