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A patient-specific aortic valve model based on moving resistive immersed implicit surfaces

Publications associées (44)

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lifex-cfd: An open-source computational fluid dynamics solver for cardiovascular applications

Alfio Quarteroni, Luca Dede', Marco Fedele

Computational fluid dynamics (CFD) is an important tool for the simulation of the cardiovascular function and dysfunction. Due to the complexity of the anatomy, the transitional regime of blood flow in the heart, and the strong mutual influence between the ...

Amsterdam2023

Compliance-matching vascular grafts with personalization potential

Georgios Rovas

Aortic diseases are characterized by dire prognosis and inadequate diagnosis, owing to their insidious yet lethal nature. Aortopathies, namely aortic aneurysms and dissections, along with certain congenital diseases, might necessitate surgical replacement ...

EPFL2023

To enforce the conservation of mass principle, a pressure Poisson equation arises in the numerical solution of incompressible fluid flow using the pressure-based segregated algorithms such as projection methods. For unsteady flows, the pressure Poisson equ ...

2023

A space-time adaptive algorithm to solve the motion of a rigid disk in an incompressible Newtonian fluid is presented, which allows collision or quasi-collision processes to be computed with high accuracy. In particular, we recover the theoretical result p ...

WALTER DE GRUYTER GMBH2021

Computational fluid dynamics of blood flow in an idealized left human heart

Alfio Quarteroni, Filippo Menghini

We construct an idealized computational model of the left human heart for the study of the blood flow dynamics in the left atrium and ventricle. We solve the Navier-Stokes equations in the ALE formulation and we prescribe the left heart wall displacement b ...

WILEY2019

High-Order Accurate Conservative Finite Difference Methods For Vlasov Equations In 2D+2V

Stephan Brunner

This manuscript discusses discretization of the Vlasov-Poisson system in 2D+2V phase space using high-order accurate conservative finite difference algorithms. One challenge confronting direct kinetic simulation is the significant computational cost associ ...

SIAM PUBLICATIONS2019

Numerical Modelling of Two-Phase Flow with Moving Boundary Fitted Meshes

Erik Gros

In this thesis, a computational approach is used to study two-phase flow including phase change by direct numerical simulation. This approach follows the interface with an adaptive moving mesh. The incompressible Navier-Stokes equations are solved, in tw ...

EPFL2018

The mathematical modeling of the heart involves several challenges, which are intrinsically related to the complexity of its function. A satisfactory cardiac model must be able to describe a wide range of different processes, such as the evolution of the t ...

EPFL2018

Propagation-based phase-contrast synchrotron imaging of aortic dissection in mice: from individual elastic lamella to 3D analysis

Nikolaos Stergiopoulos, Lydia Aslanidou, Bram Trachet, Marco Stampanoni, Patrick Segers

In order to show the advantage and potential of propagation-based phase-contrast synchrotron imaging in vascular pathology research, we analyzed aortic medial ruptures in BAPN/AngII-infused mice, a mouse model for aortic dissection. Ascending and thoraco-a ...

NATURE PUBLISHING GROUP2018

Fluid dynamics of an idealized left ventricle: the extended Nitsche's method for the treatment of heart valves as mixed time varying boundary conditions

Alfio Quarteroni, Anna Tagliabue

In this work, we study the blood flow dynamics in idealized left ventricles (LV) of the human heart modelled by the Navier-Stokes equations with mixed time varying boundary conditions. The latter are introduced for simulating the functioning of the aortic ...

Wiley2017