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Degeneration of specific neuronal populations and progressive nervous system dysfunction characterize neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. These findings are also reported in inherited diseases such as phenylke ...
The developed world is aging faster than ever before. Even in the absence of neurodegenerative disease, aging affects all kinds of human functions including perception and cognition. In most perceptual studies, one paradigm is tested and it is usually foun ...
Aging is a major risk factor for many neurological diseases and is associated with mild cognitive decline. Previous studies suggest that aging is accompanied by reduced synapse number and synaptic plasticity in specific brain regions. However, most studies ...
Increased expression of α-synuclein and point mutations in its amino acid sequence play a causative role in familial forms of Parkinson's disease (PD). In addition, circumstances affecting the level of α-synuclein expression significantly increase the risk ...
The dielectric response of hard (Fe-doped) and soft (Nb-doped) rhombohedral Pb(Zr0.58Ti0.42)1−xMexO3 (Me=Fe or Nb) ceramics was studied at subswitching conditions over a wide range of temperatures (50– 450 °C) and frequencies (10 mHz to 10 kHz). The result ...
The application of methods drawn from nonlinear and stochastic dynamics to the analysis of cardiovascular time series are applied with particular interests in the identification of changes associated with aging. Scale invariant and scale dependent approach ...
The present work investigated the effects of physical aging on interfacial adhesion and internal stresses using single-fibre model composites. First, the stress state of the interface and its evolution upon aging were studied for the microbond geometry. Th ...
A full rate-dependent constitutive theory for dynamic strain aging is developed based on two key ideas. The first idea is that both solute strengthening and forest strengthening must exist and must exhibit aging phenomena. The second idea is that a single ...
The sorption of uranium on mineral surfaces can significantly influence the fate and transport of uranium contamination in soils and groundwater. The rates of uranium adsorption and desorption on a synthetic goethite have been evaluated in batch experiment ...
Studies of the real-time dynamics of embryonic development require a gentle embryo handling method, the possibility of long-term live imaging during the complete embryogenesis, as well as of parallelization providing a population's statistics, while keepin ...