Publication
Gender-specific alteration of energy balance and circadian locomotor activity in the Crtc1 knockout mouse model of depression
Publications associées (32)
Statistical physics of periodic biological processes
Earth rotation around its axis imposes a 24-hour rhythmicity to all life on the planet.Rather than passively responding to these periodic changes, nature has given us an internal timekeeper, the circadian clock, to anticipate to our advantage the fluctuati ...
EPFL2023Human circadian rhythms and urban density: celebrating the natural day-night cycle
Marilyne Andersen, Mark Pauly, Florin Isvoranu, Megan Nicole Danell, Javier Fernandez Contreras
Our exposure to light has a key role in regulating our biological clock through a dedicated photoreceptor present in the human eye. Increased awareness to its criticality when it comes to human well-being is urgently needed, as this criticality is potentia ...
SoomeenHahm Design Ltd2021Dealing with Daily Rhythms: Families’ Strategies to Tackle Chronic Time Pressure
Vincent Kaufmann, Guillaume Simon Joseph Drevon, Philippe Gerber
As suggested by the conservation of resources theory, in contemporary societies time is considered as a limited resource in the same way as money and energy. In the current paper, a novel daily rhythm approach related to motility is presented, in order to ...
2020Sleep-wake-driven and circadian contributions to daily rhythms in gene expression and chromatin accessibility in the murine cortex
Felix Naef, Maxime Jan, Jake Yeung, Ioannis Xenarios
The timing and duration of sleep results from the interaction between a homeostatic sleep-wake-driven process and a periodic circadian process, and involves changes in gene regulation and expression. Unraveling the contributions of both processes and their ...
PNAS2019The Mouse Microbiome Is Required for Sex-Specific Diurnal Rhythms of Gene Expression and Metabolism
Felix Naef, Cédric Gobet, Frédéric Bruno Martin Gachon, Benjamin Dieter Weger, Jake Yeung
The circadian clock and associated feeding rhythms have a profound impact on metabolism and the gut microbiome. To what extent microbiota reciprocally affect daily rhythms of physiology in the host remains elusive. Here, we analyzed transcriptome and metab ...
CELL PRESS2019At the Intersection of Microbiota and Circadian Clock: Are Sexual Dimorphism and Growth Hormones the Missing Link to Pathology? Circadian Clock and Microbiota: Potential Egffect on Growth Hormone and Sexual Development
Frédéric Bruno Martin Gachon, Benjamin Dieter Weger
Reciprocal interactions between the host circadian clock and the microbiota are evidenced by recent literature. Interestingly, dysregulation of either the circadian clock or microbiota is associated with common human pathologies such as obesity, type 2 dia ...
WILEY2019Tissue-specific circadian transcriptional regulation
Circadian rhythms in physiology and behavior evolved to resonate with daily cycles in the external environment. In mammals, organs orchestrate temporal physiology over the 24-hour day, which requires extensive gene expression rhythms targeted to the right ...
EPFL2019Cross-regulatory circuits linking inflammation, high-fat diet, and the circadian clock
Felix Naef, Frédéric Bruno Martin Gachon, Jake Yeung
Mammalian physiology resonates with the daily changes in the external environment, allowing processes such as rest-activity cycles, metabolism, and body temperature to synchronize with daily changes in the surroundings. Studies have identified the molecula ...
COLD SPRING HARBOR LAB PRESS, PUBLICATIONS DEPT2018Circadian Rhythms and Mitochondria: Connecting the Dots
Carlos Canto Alvarez, Miriam Valera Alberni
Circadian rhythms provide a selective advantage by anticipating organismal nutrient needs and guaranteeing optimal metabolic capacity during active hours. Impairment of circadian rhythms is associated with increased risk of type 2 diabetes and emerging evi ...
FRONTIERS MEDIA SA2018Rhythms of the Genome: Circadian Dynamics from Chromatin Topology, Tissue-Specific Gene Expression, to Behavior
Circadian rhythms in physiology and behavior evolved to resonate with daily cycles in the external environment. In mammals, organs orchestrate temporal physiology over the 24-h day, which requires extensive gene expression rhythms targeted to the right tis ...
ELSEVIER SCIENCE LONDON2018