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Background: The restoration of complex hand functions by creating a novel bidirectional link between the nervous system and a dexterous hand prosthesis is currently pursued by several research groups. This connection must be fast, intuitive, with a high su ...
By placing axons into polymeric microchannels hosting embedded electrodes the extracellular amplitude of action potentials is greatly increased, allowing for robust recording and noise suppression. We are developing such an electrode interface to record el ...
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In the present work, a label-free, contactless and capacitive immunosensor is developed using impedance spectroscopy, in the aim to perform low-cost immunoassays. Chapter 1 puts this work in perspective with some existing techniques, while a presentation o ...
Described herein are microelectrode array devices, and methods of fabrication and use of the same, to provide highly localized and efficient electrical stimulation of a neurological target. The device includes multiple microelectrode elements arranged alon ...
The possibility of controlling dexterous hand prostheses by using a direct connection with the nervous system is particularly interesting for the significant improvement of the quality of life of patients, which can derive from this achievement. Among the ...
Recently, CMOS-based microelectrode arrays containing a high-density of electrodes have emerged as a tool enabling recording the extracellular neural electrical activity of cell cultures at subcellular resolution. However, several improvements in areas suc ...
The use of neural implants for stimulation and recording show excellent promise in restoring certain functions to the central nervous system; and neuroprostheses remains one of the most important tools of neuroscientists for the elucidation of the brain's ...
Microelectrode arrays (MEAs) are designed to monitor and/or stimulate extracellularly neuronal activity. However, the biomechanical and structural mismatch between current MEAs and neural tissues remains a challenge for neural interfaces. This article desc ...
An optimized capacitively coupled contactless conductivity detector for microchip electophoresis is presented. The detector consists of a pair of top bottom excitation electrodes and a pair of pickup electrodes disposed onto a very thin plastic microfluidi ...
This paper presents the hardware realization and modeling of high-density microelectrode arrays including both microelectronic readout amplifiers as well as three-dimensional microelectrodes forming a fully integrated CMOS compatible system enabling resear ...