Structural and functional analysis of host attachment proteins from contractile injection systems
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The present paper describes the challenges posed by transposing a successful conventional course into an – hopefully – equally successful web-based course, with the name i-Structures. This work is under way as part of the Swiss Virtual Campus project. The ...
4th International Conference on New Educational Environments2002
We introduce a simplified protein model where the water degrees of freedom appear explicitly (although in an extremely simplified fashion). Using this model we are able to recover both the warm and the cold protein denaturation within a single framework, w ...
More than 50 yr. after the proposal of the Dewar-Chatt-Duncanson model for the binding of olefins to transition-metal atoms, the first structurally characterized example of a silver-C2H4 complex [Ag(h2-C2H4)3]+ was obtained with the help of the very weakly ...
The simulation of polymer-dispersed cholesteric liquid crystals is carried out using a model, which takes into account the domain structure of the layer. The model is based on the 4x4 matrix calculation method of Berreman. One considers different orientati ...
SPIE-The International Society for Optical Engineering, Bellingham, USA2003
We present mol. dynamics simulations of bovine rhodopsin in a membrane mimetic environment based on the recently refined x-ray structure of the pigment. The interactions between the protonated Schiff base and the protein moiety are explored both with the c ...
The three-dimensionally modulated incommensurate crystal structure of lazurite from the Baikal region was determined for the first time. The structure was solved within the cubic system with the unit-cell parameter a(cub) = 9.077(1) Angstrom and the (3+2)- ...
An extensive random mutagenesis study on the function of nine residues in the subunit binding site of FimC was conducted to evaluate the mol. mechanisms of subunit binding by FimC and the contribution of chaperone surface residues. Five plasmid libraries o ...
Deutsche Akademie der Naturforscher Leopoldina2001
Secretins, a superfamily of multimeric outer membrane proteins, mediate the transport of large macromolecules across the outer membrane of Gramnegative bacteria. Limited proteolysis of secretin PulD from the Klebsiella oxytoca pullulanase secretion pathway ...
The hybG gene product from Escherichia coli has been identified as a chaperone-like protein acting in the maturation of hydrogenases 1 and 2. It was shown that HybG forms a complex with the precursor of the large subunit of hydrogenase 2. As with HypC, whi ...