Advantages of soft subdural implants for the delivery of electrochemical neuromodulation therapies to the spinal cord
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Spinal cord stimulation (i.e. the electrical stimulation of the dorsal columns of the spinal cord) isincreasingly used for the treatment of intractable pain syndromes due to vascular or neurogenicdisorders. Despite well-established safety and efficacy in p ...
Locomotor training improves function after a spinal cord injury both in experimental and clinical settings. The activity-dependent mechanisms underlying such improvement, however, are sparsely understood. Adult rats received a complete spinal cord transect ...
Robot assisted therapy is a rapidly growing field of rehabilitation. The MotionMaker™ is a new type of a stationary test and training system for the lower limbs combining two motorised hip-knee-ankle-foot orthoses equipped with position and torque sensors ...
We hypothesized that epidural spinal cord stimulation (ES) and quipazine (a serotonergic agonist) modulates the excitability of flexor and extensor related intraspinal neural networks in qualitatively unique, but complementary, ways to facilitate locomotio ...
Spinal cord injuries (SCIs) in humans and experimental animals are often associated with varying degrees of spontaneous functional recovery during the first months after injury. Such recovery is widely attributed to axons spared from injury that descend fr ...
Background Physical and functional losses due to aging and diseases decrease human mobility, independence, and quality of life. This study is aimed at summarizing and quantifying these losses in order to motivate solutions to overcome them with a special f ...
Changes in epidurally induced (S1) spinal cord reflexes were studied as a function of the level of restoration of stepping ability after spinal cord transection (ST). Three types of responses were observed. The early response (ER) had a latency of 2.5 to 3 ...
