Decellularised tissues obtained by a CO2-philic detergent and supercritical CO2
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Decellularized extracellular matrix (ECM) derived scaffolds serve as potential candidates in the application of cartilage regeneration to guide cells into proliferating and maintaining the structural zones of articular cartilage. ECM tissue matrices offer fr ...
Everyday life physiological functions such as breathing, muscle contraction, and blood circulation rely on the ability of single cells to organize into higher complexity structures and sustain mechanical deformations. Cell monolayers are the simplest tissu ...
The present invention relates to methods of derivation and/or propagation of epithelial cells from tissue comprising culturing said tissue in media containing an effective amount of a proprotein convertase inhibitor for a period of time allowing the deriva ...
The recapitulation of tissue organization and function in vitro is one of the main objectives of tissue engineering. Proper tissue function depends on the spatial assembly and interactions between key components such as cells, growth factors, signaling cue ...
EPFL2016
The majority of muscles, nerves, and tendons are composed of fiber-like fascicle morphology. Each fascicle has a) elongated cells highly aligned with the length of the construct, b) a high volumetric cell density, and c) a high length-to-width ratio with a ...
Ureteral replacement by tissue engineering might become necessary following tissue loss after excessive ureteral trauma, after retroperitoneal cancer, or even after failed reconstructive surgery. This need has driven innovation in the design of novel scaff ...
An overview of the optical methods available to modulate the cellular activity in cell cultures and biological tissues is presented, with a focus on the use of exogenous functional materials that absorb electromagnetic radiation and transduce it into a sec ...
Laser-induced optical breakdown (LIOB) is a multiphoton process which can be used for selective removal of material. It revolves around the creation of a plasma in the focal volume of a beam, and requires very high peak intensities in the order of the GW.c ...
Humpback whales, like other polar wildlife, accumulate persistent organic pollutants. In Southern hemisphere populations, hexachlorobenzene (HCB) dominates the contaminant profiles. HCB is linked to a variety of health effects and is classified as a group ...
Articular cartilage, together with skin, was predicted to be one of the first tissues to be successfully engineered. However cartilage repair remains nowadays still elusive, as we are still not able to overcome the hurdles of creating biomaterials correspo ...