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A Process for Digitizing and Simulating Biologically Realistic Oligocellular Networks Demonstrated for the Neuro-Glio-Vascular Ensemble

Publications associées (34)

A Brief History of Simulation Neuroscience

Our knowledge of the brain has evolved over millennia in philosophical, experimental and theoretical phases. We suggest that the next phase is simulation neuroscience. The main drivers of simulation neuroscience are big data generated at multiple levels of ...

FRONTIERS MEDIA SA2019

Dynamic organization of human brain function and its relevance for psychosis vulnerability

Daniela Maria Zöller

The brain is the substrate of a complex dynamic system providing a remarkably varied range of functionalities, going from simple perception to higher-level cognition. Disturbances in its complex dynamics can cause an equally vast variety of mental disorder ...

EPFL2019

Norepinephrine stimulates glycogenolysis in astrocytes to fuel neurons with lactate

Pierre Magistretti, Henry Markram, Felix Schürmann, Daniel Keller, Jay Coggan, Corrado Cali

Although efficient compared to computers, the human brain utilizes energy at 10-fold the rate of other organs by mass. How the brain is supplied with sufficient on-demand energy to support its activity in the absence of neuronal storage capacity remains un ...

2018

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The integration of renewable energy technologies and building renovation are the two main procedures for improving energy sustainability of buildings at neighborhood scale. It is difficult, however, to optimize these procedures simultaneously. This study f ...

Elsevier2018

Integrating hourly life-cycle energy and carbon emissions of energy supply in buildings

Didier Albert Simon Vuarnoz, Thomas Bernard Paul Jusselme, Stefano Cozza, Philippe Couty

Huge amount of energy resources greenhouse gas (GHG) emissions is devoted to the built environment. Therefore, an accurate assessment method of these indicators is compulsory. To take advantage of the temporal variation in the primary energy use and associ ...

2018

Standard algorithm of building’s energy strategy often use electricity and its tariff as the sole criterion of choice. This paper introduced an algorithmic regulation using global warming potential (GWP) of energy flux, to select which installation will sa ...

IOP Conference Series2018

Energy Efficiency and Integration in the Refining and Petrochemical Industries

Laurent Gabriel Félix Alexandre Stéphane Bungener

Industrial sites and their associated energy systems are estimated to be responsible for 31% of worldwide energy consumption. Improving their energy efficiencies has the potential to reduce production costs of industrial sites and contribute towards the 20 ...

EPFL2016

A Cellular Perspective on Brain Energy Metabolism and Functional Imaging

Pierre Magistretti, Igor Allaman

The energy demands of the brain are high: they account for at least 20% of the body's energy consumption. Evolutionary studies indicate that the emergence of higher cognitive functions in humans is associated with an increased glucose utilization and expre ...

Elsevier2015

Glucose is the main energy substrate for the brain. There is now extensive evidence indicating that the metabolic profile of neural cells with regard to glucose utilization and glycolysis rate is not homogenous, with a marked propensity for glycolytic gluc ...

Frontiers Research Foundation2015

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Brain imaging is becoming an important field in the frame of the neurophotonics in correlations with other medical ones in neuroscience studying functional and morphological aspects. In this presentation an overview on multi photon imaging of the brain wil ...

Spie-Int Soc Optical Engineering2015

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