Publications associées à Interferon lambda 3/4 polymorphisms are associated with AIDS-related Kaposi's sarcoma

PSGL-1 is an evolutionarily conserved antiviral restriction factor

The arms race between viruses and their hosts shaped the evolutionary history and the genome composition of both parties. Restriction factors are the first-line antiviral effectors encoded by the host genomes and are often conserved through evolution to pr ...

AMER SOC MICROBIOLOGY2023

Environmental determinants of access to shared sanitation in informal settlements: a cross-sectional study in Abidjan and Nairobi

Jérôme Chenal, Vitor Pessoa Colombo, Jürg Utzinger

Background Universal access to basic sanitation remains a global challenge, particularly in low- and middle-income countries. Efforts are underway to improve access to sanitation in informal settlements, often through shared facilities. However, access to ...

2023

A Baseline Cellular Antiviral State Is Maintained by cGAS and Its Most Frequent Naturally Occurring Variant rs610913

Jacques Fellay, Christian Axel Wandall Thorball, Shuting Xu

Upon recognition of aberrantly located DNA, the innate immune sensor cyclic GMP-AMP synthase (cGAS) activates stimulator of IFN genes (STING)/IFN regulatory factor (IRF)3-driven antiviral responses. In this study, we characterized the ability of a specific ...

AMER ASSOC IMMUNOLOGISTS2022

Phase separation in viral infections

Christina Ernst, Haohua Li

Viruses rely on the reprogramming of cellular processes to enable efficient viral replication; this often requires subcompartmentalization within the host cell. Liquid-liquid phase separation (LLPS) has emerged as a fundamental principle to organize and su ...

ELSEVIER SCI LTD2022

Genetic variation near CXCL12 is associated with susceptibility to HIV-related non-Hodgkin lymphoma

Jacques Fellay, Christian Axel Wandall Thorball, Christian Hammer

Human immunodeficiency virus (HIV) infection is associated with an increased risk of non-Hodgkin lymphoma (NHL). Even in the era of suppressive antiretroviral treatment, HIV-infected individuals remain at higher risk of developing NHL compared to the gener ...

FERRATA STORTI FOUNDATION2021

Rapid Progression of Kidney Dysfunction in People Living With HIV: Use of Polygenic and Data Collection on Adverse Events of Anti-HIV Drugs (D:A:D) Risk Scores

Jacques Fellay, Christian Axel Wandall Thorball

Background In people with human immunodeficiency virus (PWH), it is unknown whether genetic background associates with rapid progression of kidney dysfunction (ie, estimated glomerular filtration rate [eGFR] decrease of >5mL/min/1.73m(2) per year for >= 3 ...

OXFORD UNIV PRESS INC2021

Use of deoxysphingolipids as anti-toxins and anti-virals

Françoise Gisou van der Goot Grunberg

The present invention relates 1-deoxysphingolipids, as well as pharmaceutically acceptable salts thereof, for use in the prevention and/or treatment of intoxication or viral infections, in particular 1-deoxyceramide or a 1-deoxysphingoid base prodrug there ...

2020

Sulfonated Nanomaterials with Broad-Spectrum Antiviral Activity Extending beyond Heparan Sulfate-Dependent Viruses

Francesco Stellacci, Matteo Gasbarri, Valeria Cagno, Chiara Medaglia

Viral infections are among the main causes of death worldwide, and we lack antivirals for the majority of viruses. Heparin-like sulfated or sulfonated compounds have been known for decades for their ability to prevent infection by heparan sulfate proteogly ...

AMER SOC MICROBIOLOGY2020

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Interferon lambda 3/4 polymorphisms are associated with AIDS-related Kaposi's sarcoma

Virucidal compositions and use thereof

PSGL-1 is an evolutionarily conserved antiviral restriction factor

Environmental determinants of access to shared sanitation in informal settlements: a cross-sectional study in Abidjan and Nairobi

A Baseline Cellular Antiviral State Is Maintained by cGAS and Its Most Frequent Naturally Occurring Variant rs610913

Phase separation in viral infections

Genetic variation near CXCL12 is associated with susceptibility to HIV-related non-Hodgkin lymphoma

Rapid Progression of Kidney Dysfunction in People Living With HIV: Use of Polygenic and Data Collection on Adverse Events of Anti-HIV Drugs (D:A:D) Risk Scores

How to detect and reduce potential sources of biases in studies of SARS-CoV-2 and COVID-19

Use of deoxysphingolipids as anti-toxins and anti-virals

Sulfonated Nanomaterials with Broad-Spectrum Antiviral Activity Extending beyond Heparan Sulfate-Dependent Viruses

Graph Chatbot

Chattez avec Graph Search

PSGL-1 is an evolutionarily conserved antiviral restriction factor

Sulfonated Nanomaterials with Broad-Spectrum Antiviral Activity Extending beyond Heparan Sulfate-Dependent Viruses

Virucidal compositions and use thereof

Genetic variation near CXCL12 is associated with susceptibility to HIV-related non-Hodgkin lymphoma

A Baseline Cellular Antiviral State Is Maintained by cGAS and Its Most Frequent Naturally Occurring Variant rs610913

Environmental determinants of access to shared sanitation in informal settlements: a cross-sectional study in Abidjan and Nairobi

Phase separation in viral infections

How to detect and reduce potential sources of biases in studies of SARS-CoV-2 and COVID-19

Use of deoxysphingolipids as anti-toxins and anti-virals

Rapid Progression of Kidney Dysfunction in People Living With HIV: Use of Polygenic and Data Collection on Adverse Events of Anti-HIV Drugs (D:A:D) Risk Scores