Publication

Blocking probability of large wood and resulting head increase at ogee crest spillways

Publications associées (38)

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ISSCR standards for the use of human stem cells in basic research

Matthias Lütolf

The laboratory culture of human stem cells seeks to capture a cellular state as an in vitro surrogate of a biological system. For the results and outputs from this research to be accurate, meaning-ful, and durable, standards that ensure reproducibility and ...

Cambridge2023

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Separating cells from the body and cultivating them in vitro will alter the function of cells. Therefore, for optimal cell culture in the laboratory, conditions similar to those of their natural growth should be provided. In previous studies, it has been s ...

2021

Blockage Probability Modeling of Large Wood at Reservoir Spillways With Piers

Anton Schleiss, Michael Pfister, José Pedro Gamito de Saldanha Calado Matos, Paloma Furlan

Large wood increases the morphological and hydraulic complexity of rivers, yet it may block and modify the flood discharge capacity of hydraulic structures. To assess the related risk, blockage probability estimation for hydraulic structures such as reserv ...

2021

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The blockage of weirs or bridges by in-stream wood can reduce the flood discharge capacity, leading to hazardous situations. To assess the related risk, blocking probabilities quantifications are needed. However, large wood has a random behaviour and it is ...

SPRINGER2020

Engineered signaling centers for the spatially controlled patterning of human pluripotent stem cells

Matthias Lütolf, Felix Naef, Yoji Tabata, Eric Paquet, François Réal Rivest, Ambroise Roger Vuaridel, Andrea Manfrin

Signaling centers, localized groups of cells that secrete morphogens, play a key role in early development and organogenesis by orchestrating spatial cell fate patterning. Here we present a microfluidic approach that exposes human pluripotent stem cell (hP ...

NATURE PUBLISHING GROUP2019

Hematopoietic stem cells (HSC) are responsible for the life-long maintenance of our blood system. Their long-term capacity to both self-renew and differentiate and the ability to efficiently âhomeâ to their bone marrow niches when injected in the blood ...

EPFL2018

Hematopoietic stem cells (HSCs) are responsible for the continuous production of all blood cells. This unique ability has made it possible to successfully use HSCs in the clinical setting to remedy various blood disorders. However, despite six decades of r ...

EPFL2018

In vivo modeling of human neuron dynamics and Down syndrome

Graham Knott

Harnessing the potential of human stem cells for modeling the physiology and diseases of cortical circuitry requires monitoring cellular dynamics in vivo. We show that human induced pluripotent stem cell (iPSC)-derived cortical neurons transplanted into th ...

AMER ASSOC ADVANCEMENT SCIENCE2018

Spillway blockage caused by large wood in reservoirs

Anton Schleiss, Michael Pfister, José Pedro Gamito de Saldanha Calado Matos, Paloma Furlan

Large wood (LW) elements are often transported by rivers into reservoirs during heavy rainfall events. Large wood has important environmental attributes that benefit the diversification of riverine ecosystems. There are several studies dealing with the tra ...

E3S Web of Conferences2018

Although stem cells hold tremendous potential for clinical applications, their in vitro manipulation remains very challenging. In vivo, stem cells reside in intricate 3D microenvironments, termed niche, in which many local and systemic extrinsic factors ar ...

EPFL2017