Development of Tissue Kallikrein Inhibitors for the Treatment of Netherton Syndrome
Publications associées (36)
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BACKGROUND: The Ras and Notch signaling pathways are frequently activated during development to control many diverse cellular processes and are often dysregulated during tumorigenesis. To study the role of Notch and oncogenic Kras signaling in a progenitor ...
Carbon-epoxy prepregs are generally used to form the skins of honeycomb sandwich structures used in aerospace or racing yachts. For some applications, it is desirable to increase the thickness of the skins. In order to achieve an ideal core pressure level ...
The skin wrinkling phenomenon was investigated in case of ultralight sandwich structures with honeycomb core manufactured by one shot vacuum bag processing. A relation between process pressure and compressive strength of the skin was established. ...
FEUP, Porto, Portugal2008
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Primary lymphedema is a congenital pathology of dysfunctional lymphatic drainage characterized by swelling of the limbs, thickening of the dermis, and fluid and lipid accumulation in the underlying tissue. Two mouse models of primary lymphedema, the Chy mo ...
American Society for Investigative Pathology2010
Vacuum-bag processing of honeycomb sandwich structures faces particular challenges compared to autoclave sandwich fabrication for aeronautics, a consequence of using, at the most, atmospheric pressure for their manufacturing. In particular, the adhesion of ...
EPFL2009
Non-autoclave processing of honeycomb sandwich structures generally leads to poor compaction and high porosity of the skins, along with a decreased skin-core adhesion. The pressure level inside the honeycomb cells plays an important role and is controlled ...
Elsevier2010
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Decreased interstitial flow (IF) in secondary lymphedema is coincident with poor physiological lymphatic regeneration. However, both the existence and direction of causality between IF and lymphangiogenesis remain unclear. This is primarily because the rol ...
2007
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Skin tones, portraits in particular, are of critical importance in photography and video, but a number of factors, such as pigmentation irregularities (e.g., moles, freckles), irritation, roughness, or wrinkles can reduce their appeal. Moreover, such “defe ...
2010
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The skin wrinkling phenomenon was investigated in the case of ultra-light sandwich structures with a honeycomb core manufactured by one-shot vacuum bag processing. The interplay between process pressure and compressive strength of the skin was established. ...
2009
Non-autoclave processing of honeycomb sandwich structures generally leads to poor compaction and high porosity of the skins along with a decreased skin-core adhesion. Air permeability of the skins, a critical parameter of low pressure processing, is often ...
