MATHICSE Technical Report : Integrated Heart – Coupling multiscale and multiphysics models for the simulation of the cardiac function
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The most important physiological mechanism mediating enhanced exercise performance is increased sympathetic, beta adrenergic receptor (beta-AR), and adenylyl cyclase (AC) activity. This is the first report of decreased AC activity mediating increased exerc ...
In this project we numerically simulate electrophysiological models for cardiac applications by means of Isogeometric Analysis. Specifically, we aim at understanding the advantages of using high order continuous NURBS (Non-UniformRational B-Splines) basis ...
In this Master thesis we aim at studying some physiological and computational aspects of the excitation-contraction mechanisms in the heart muscle. This phenomenon exhibits many complexities at different spatio-temporal scales. The relevance and applicabil ...
The invention of heart pacemakers in the 50's aims to help patients to overcome heart strokes, which represent the first cause of death worldwide. In Europe and in the USA, more than 3000 pacemakers are implanted every day. Despite the constant evolution o ...
In this work, we study the blood flow dynamics in idealized left ventricles (LV)of the human heart modelled by the Navier-Stokes equations with mixed time varying boundary conditions (BCs). The latter are introduced for simulating the functioning of the ao ...
The project deals with the finite element approximation of the monodomain equation, which models the propagation of the electrical potential in the cardiac muscle through a coupled system of PDE’s. The goal is to recover the shape of an infarcted area insi ...
Regeneration of lost myocardium is an important goal for future therapies because of the increasing occurrence of chronic ischemic heart failure and the limited access to donor hearts. An example of a treatment to recover the function of the heart consists ...
Estimating the respiratory rate (RR) from the electrocardiogram (ECG) is of interest as the direct measurement of the respiration in clinical situations is often cumbersome. In this study, the RR was estimated from the multi-lead ECG R-peak amplitude (RPA) ...
Cardiac and skeletal muscle function relies on a continuous energy production via fatty acid metabolism and mitochondrial oxidation of pyruvate, with a fine balance between substrate delivery and utilization. Changes in metabolism are increasingly being im ...
Numerical modeling of the human cardiovascular system (CVS) represents an active branch of research which allows the medical specialists to advance in understanding of underlined processes of blood circulation and the heart work at any scale, moreover, it ...
