Sleep-wake-driven and circadian contributions to daily rhythms in gene expression and chromatin accessibility in the murine cortex
Publications associées (126)
Graph Chatbot
Chattez avec Graph Search
Posez n’importe quelle question sur les cours, conférences, exercices, recherches, actualités, etc. de l’EPFL ou essayez les exemples de questions ci-dessous.
AVERTISSEMENT : Le chatbot Graph n'est pas programmé pour fournir des réponses explicites ou catégoriques à vos questions. Il transforme plutôt vos questions en demandes API qui sont distribuées aux différents services informatiques officiellement administrés par l'EPFL. Son but est uniquement de collecter et de recommander des références pertinentes à des contenus que vous pouvez explorer pour vous aider à répondre à vos questions.
Background: Parkinson's disease (PD) is a neurodegenerative disorder resulting in motor disturbances that can impact normal gait. Although PD initially responds well to pharmacological treatment, as the disease progresses efficacy often fluctuates over the ...
Sleep/wake classification systems that rely on phys- iological signals suffer from inter-subject differences that make accurate classification with a single, subject-independent model difficult. To overcome the limitations of inter-subject variability we s ...
Institute of Electrical and Electronics Engineers2010
Objectives: The main energy reserve of the brain is glycogen, which is almost exclusively localized in astrocytes. We previously reported that cerebral expression of certain genes related to glycogen metabolism changed following instrumental sleep deprivat ...
Increased fatigue of pilots during long flights can place both humans and machine at high risk. In this paper, we describe our research on a SymBodic (SYMbiotic BODies) system designed to minimize pilot fatigue in a simulated 48 hour mission. The system de ...
IEEE Engineering in Medicine and Biology Society2010
We describe a method for the online classification of sleep/wake states based on cardiorespiratory signals produced by wearable sensors. The method was conceived in view of its applicability to a wearable sleepiness monitoring device. The method uses a Fas ...
Sleep problems and disorders have a serious impact on human health and wellbeing. The rising costs for treating sleep-related chronic diseases in industrialized countries demands efficient prevention. Low-cost, wearable sleep / wake detection systems which ...
Precision is a crucial property of noisy circadian oscillators that can be quantified by the quality factor (Q). Until now, deterministic properties of circadian oscillations like the period or amplitude attracted most of the attention while relatively few ...
BACKGROUND: Organisms are able to anticipate changes in the daily environment with an internal oscillator know as the circadian clock. Transcription is an important mechanism in maintaining these oscillations. Here we explore, using whole genome tiling arr ...
Background: Fluorescent and bioluminescent time-lapse microscopy approaches have been successfully used to investigate molecular mechanisms underlying the mammalian circadian oscillator at the single cell level. However, most of the available software and ...