Microfluidics as an Enabling Technology for Personalized Cancer Therapy
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The present invention relates to a method and a kit for predicting the efficacy of cancer therapy in a subject who has undergone or is undergoing chemotherapy treatment for cancer. ...
Head and neck (H&N) cancer patients have a high incidence of second primary tumors in the tracheobronchial tree. Diagnostic autofluorescence endoscopy (DAFE) has shown promising results in the detection of early neoplastic and pre-neoplastic changes in the ...
The present invention relates to derivatives of dihydroxypyrrolidine useful in the treatment of cancer. The invention further relates to a process for making the compounds. The compounds are inhibitors of alpha mannosidase, and possibly, also inhibit nicot ...
BACKGROUND: High-throughput gene expression profiling technologies generating a wealth of data, are increasingly used for characterization of tumor biopsies for clinical trials. By applying machine learning algorithms to such clinically documented data set ...
The present invention relates to novel organometallic compds. for use as a medicine, in particular in photodynamic therapy against various diseases, such as cancer. The compds. comprise a central porphyrin or phthalocyanine backbone to which ligand linkers ...
Cancer: growth caused by uncontrolled and abnormal cell division, resulting in a non-structured mass or tumor, serving no beneficial purpose to the body. Even though cancer is one of the leading fatal diseases of today's world, with no distinction for age, ...
The present invention relates to organometallic compounds useful in the treatment of metastasis. The organometallic compounds comprise a ligand that is convalently bound to a bioactive compound, which is an inhibitor of a resistance pathway or a derivative ...
Meta(tetrahydroxyphenyl)chlorin (m-THPC) is a new photosensitizer currently undergoing clin. trials at Lausanne's CHUV hospital for photodynamic therapy (PDT) of early cancer in the upper aerodigestive tract. The illumination of m-THPC with light at 650 nm ...
The mammalian intestine has one of the highest turnover rates in the body. The intestinal epithelium is completely renewed in less than a week. It is divided into spatially distinct compartments in the form of finger-like projections and invaginations that ...
The detection of chromosomal aberrations constitutes an important stage in the comprehension of the pathogenesis of several diseases, as cancer. In this case, the amplification or deletion (suppression) of some chromosomal regions, was identified as being ...
