Large-scale kinetic metabolic models of Pseudomonas putida KT2440 for consistent design of metabolic engineering strategies
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Recent advancements in metabolomics and fluxomics methods and ever-increasing amount of available experimental data necessitate systems-oriented methodologies for efficient and systematic integration of data into consistent large-scale kinetic models capab ...
Genome-scale metabolic reconstructions (GSMRs) are valuable resources in the analysis and understanding of cellular metabolism. They are based on genome sequence and annotation, and they are to develop bottom-up mathematical models of metabolic networks. T ...
This report reviews recent developments in ethylbenzene (EB) manufacturing technologies and studies in detail the suggested process; Production of Ethylbenzene via Side Alkylation of Toluene by Methanol. The desired amount of ethylbenzene as the product is ...
Genome-scale metabolic reconstructions have become indispensable tools for understanding and investigation of the metabolism of any organism in this post-genomic era. However, there are still knowledge gaps in our understanding of the metabolism of even th ...
A review with 11 refs. offers a perspective on the challenges posed by bioinformatics and functional genomics. Bioinformatics here is defined as the development and implementation of computational tools and frameworks for the management, anal. and interpre ...
The beginning of this millennium has been marked by some remarkable scientific events, notably the completion of the first objective of the Human Genome Project [HGP], i.e., the decoding of the 3 billion bases that compose the human genome. This success ha ...
With the sequencing and annotation of the entire genomes of numerous microorganisms has come the advent of the genome scale metabolic models such as the iJR904 model of E. coli from Palsson and coworkers. Metabolic flux anal. (MFA) is widely employed to ge ...
