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A perspective view on the nanomotion detection of living organisms and its features

Publications associées (41)

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Wireless Sensor Networks (WSNs) are collections of sensing devices using wireless communication to exchange data. In the past decades, steep advancements in the areas of microelectronics and communication systems have driven an explosive growth in the depl ...

EPFL2018

AFM contribution to unveil pro- and eukaryotic cell mechanical properties

Giovanni Dietler, Sandor Kasas, Petar Stupar

Atomic force microscopy is nowadays a well-established technique that permits the investigation of numerous parameters of living matter. In particular, it allows the exploration of the mechanical properties of living organisms in almost physiological condi ...

Elsevier2018

DNA-protein interactions explored by atomic force microscopy

Giovanni Dietler, Sandor Kasas

DNA-protein interactions play an important role in all living organisms on Earth. The advent of atomic force microscopy permitted for the first time to follow and to characterize interaction forces between these two molecular species. After a short descrip ...

Elsevier2018

Organometallic Glutathione S-Transferase Inhibitors

Paul Joseph Dyson, Rosario Scopelliti, Mylène Soudani, Emilia Paunescu

A new family of organometallic p-cymene ruthenium(II) and osmium(II) complexes conjugated to ethacrynic acid, a glutathione transferase (GST) inhibitor, is reported. The ethacrynic acid moiety (either one or two) is tethered to the arene ruthenium(II) and ...

2017

Precision global health in the digital age

Marcel Salathé, Idris Guessous, Gérard Escher

Precision global health is an approach similar to precision medicine, which facilitates, through innovation and technology, better targeting of public health interventions on a global scale, for the purpose of maximising their effectiveness and relevance. ...

EMH Swiss Medical Publishers, Ltd.2017

Regulated intramembrane proteolysis of the AXL receptor kinase generates an intracellular domain that localizes in the nucleus of cancer cells

Patrick Fraering

Deregulation of the TAM (TYRO3, AXL, and MERTK) family of receptor tyrosine kinases (RTKs) has recently been demonstrated to predominately promote survival and chemoresistance of cancer cells. Intramembrane proteolysis mediated by presenilin/gamma-secretas ...

Federation Amer Soc Exp Biol2017

Optimization and characterization of the endogenous production of protoporphyrin IX in a yeast model

Georges Wagnières, Jaroslava Joniová, Emmanuel Louis Arthur Gerelli, Matthieu Philippe Emmanuel Zellweger

The availability of reproducible, convenient, and inexpensive model organisms able to generate predictable levels of endogenous porphyrins, including protoporphyrin IX (PpIX), is essential in photomedicine research. Saccharomyces cerevisiae produces endoge ...

Spie-Soc Photo-Optical Instrumentation Engineers2016

The clinical development of anticancer metallodrugs is often hindered by the elusive nature of their molecular targets. To identify the molecular targets of an antimetastatic ruthenium organometallic complex based on 1,3,5-triaza-7-phosphaadamantane (RAPTA ...

2015

Implementation of analytical methods for biological samples (e.g. bacteria or mammalian cells) is of great importance for diagnosis and treatment of various diseases, as well as for environmental monitoring. However, analysing biological samples is a cumbe ...

EPFL2015

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A series of arene ruthenium metalla-rectangles of general formula (eta(6)-p-cymene)(4)Ru-4(mu(4)-embelin)(2)(mu(2)-N boolean AND N)(2)(4) was prepared from the embelin-derived metalla-clip (eta(6)-p-cymene)(2)Ru-2(mu(4)-embelin) Cl-2 (1), silver ...

Elsevier Science Sa2015