Acoustic Resonators for Intracellular Tagging

Cell migration has always been essential for understanding the underlying mechanisms of physiological phenomena. For this reason, many diverse cell tracking methods are presented in literature, such as optical imaging, MRI and radionuclear imaging. However, optical methods are invasive and MRI and radionuclear imaging suffer from low spatial resolution. To overcome the limits imposed by state of the art cell tracking technologies, we propose to use plate acoustic wave resonators as a novel method for tagging single cells and tracking their spatio-temporal dynamics. In this work, we investigate and optimize the design of these tags, using finite element modelling simulations.