Dynamic time domain near-infrared optical tomography based on a SPAD camera
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Confocal microscopes use photomultiplier tubes and hybrid detectors due to their large dynamic range, which typically exceeds the one of single-photon avalanche diodes (SPADs). The latter, due to their photon counting operation, are usually limited to an o ...
A major problem for optical biomedical imaging methods, e.g. near-infrared optical tomography (NIROT), using time resolved SPAD sensors is a slow acquisition time, resulting in motion artefacts and decreased patient comfort. We present a new SPAD sensor mo ...
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EPFL2015
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Single-photon avalanche diodes (SPADs) can be integrated into large pixel arrays. The aim of this paper is to present a view on how these imagers change the paradigm of wide-field near-infrared imaging (NIRI). Thanks to the large number of pixels that they ...
Questions such as biomolecular interactions, kinetics of enzymes, DNA conformational changes, cellular structures properties (among others) are addressed by characterizing the biological function of molecules. This function depends on their structure and t ...
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EPFL2013
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