Vascular-targeted micelles as a specific MRI contrast agent for molecular imaging of fibrin clots and cancer cells
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Metastatic growth in distant organs is the major cause of cancer mortality. The development of metastasis is a multistage process with several rate-limiting steps. Although dissemination of tumour cells seems to be an early and frequent event, the successf ...
Magnetic resonance imaging (MRI) technique is at the forefront of biomedical and clinical imaging. Its superb spatial resolution, noninvasive nature and use of benign radiation outweigh its intrinsic low detection sensitivity. However paramagnetic relaxers ...
Tumors consist of cells whose growth and morphological characteristics are markedly different from those of normal cells. Observation of human and animal models argue that tumor development proceeds via a process formally analogous to Darwinian evolution, ...
We investigated iron oxide nanoparticles with two different surface modifications, dextran coating and cross-linked dextran coating, showing that their different internalization affects their capability to enhance radiation damage to cancer cells. The inte ...
Fluorescence cystoscopy has been recently acknowledged as a useful method to detect early superficial bladder cancer, even flat lesions. After the instillation of hexaminolevulinic acid (Hexvix®) in the bladder for about an hour, photoactivable porphyrins ...
Spie-Int Soc Optical Engineering, Po Box 10, Bellingham, Wa 98227-0010 Usa2009
Nanoparticles may provide advanced biomedical research tools based on polymeric or inorganic formulations or a combination of both. They have the potential to be used in many different biological and medical applications as in diagnostic tests assays for e ...
Fluorescence cystoscopy has been recently acknowledged as a useful method to detect early superficial bladder cancer, even flat lesions. After the instillation of hexaminolevulinic acid (Hexvix®) in the bladder for about an hour, photoactivable porphyrins ...
A new approach to quantitative single-molecule imaging by confocal laser scanning microscopy (CLSM) is presented. it relies on fluorescence intensity distribution to analyze the molecular occurrence statistics captured by digital imaging and enables direct ...
We present an effective solution for the problem of contrast enhancement in phase-contrast microangiography, with the specific objective of visualising small (< 8 A mu m) vessels in tumor-related microangiogenesis. Different hydrophilic and hydrophobic con ...
Nanoparticles may provide advanced biomedical research tools based on polymeric or inorganic formulations or a combination of both. They have the potential to be used in many different biological and medical applications as in diagnostic tests assays for e ...
