Publication

Mechanistic studies of DNP and applications of hyperpolarized probes to study renal physiology and metabolism

Publications associées (96)

Graph Chatbot

Chattez avec Graph Search

Posez n’importe quelle question sur les cours, conférences, exercices, recherches, actualités, etc. de l’EPFL ou essayez les exemples de questions ci-dessous.

AVERTISSEMENT : Le chatbot Graph n'est pas programmé pour fournir des réponses explicites ou catégoriques à vos questions. Il transforme plutôt vos questions en demandes API qui sont distribuées aux différents services informatiques officiellement administrés par l'EPFL. Son but est uniquement de collecter et de recommander des références pertinentes à des contenus que vous pouvez explorer pour vous aider à répondre à vos questions.

Connectez-vous pour utiliser Chat avec Graph Search

Carbazole as Linker for Dinuclear Gadolinium-Based MRI Contrast Agents

Lothar Helm, Anne-Sophie Chauvin, Loïck Moriggi, Bibimaryam Mousavi

Ligands able to complex two gadolinium ions have been synthesized and characterized in view of the ability of the complexes to increase the spin relaxation of water protons. All ligands are based on the heptadentate diethylenetriaminetetraacetic acid (DTTA ...

Wiley-V C H Verlag Gmbh2017

We have recently demonstrated, in the context of para-hydrogen induced polarization (PHIP), the conversion of hyperpolarized proton singlet order into heteronuclear magnetisation can be efficiently achieved via a new sequence named S2hM (Singlet to heteron ...

2017

Nuclear Magnetic Resonance (NMR) is one of the most versatile techniques since it enables the characterization of solid, liquid and gaseous systems in a plethora of in-vitro and in-vivo experiments. Despite its multidisciplinary scope, it still suffers fro ...

EPFL2016

, ,

A method for the preparation of a hyperpolarized solution of molecules comprises the steps: 1) suspending or coating of a micro-particulate matrix, which is comprising or consisting of the molecules, with a glass-forming solution or suspension comprising a ...

2016

, , , ,

Hyperpolarization by dissolution dynamic nuclear polarization (DNP) is a versatile technique to dramatically enhance the nuclear magnetic resonance (NMR) signal intensity of insensitive long-T1 nuclear spins such as 6 Li. The 6 Li longitudinal relaxation o ...

Wiley-Blackwell2016

, , , ,

We present direct local-probe evidence for strongly hybridized nuclear-electronic spin states of an Ising ferromagnet LiHoF4 in a transverse magnetic field. The nuclear-electronic states are addressed via a magnetic resonance in the GHz frequency range usi ...

2016

Hyperpolarization of Frozen Hydrocarbon Gases by Dynamic Nuclear Polarization at 1.2 K

David Lyndon Emsley, Geoffrey Bodenhausen, Aurélien Bornet, Sami Jannin, Jonas Milani, Basile Vuichoud, Estel Canet Martinez, David Benjamin Roger Antoine Gajan, David Baudouin

We report a simple and general method for the hyperpolarization of condensed gases by dynamic nuclear polarization (DNP). The gases are adsorbed in the pores of structured mesoporous silica matrices known as HYPSOs (HYper Polarizing SOlids) that have param ...

2016

Rational design of dinitroxide biradicals for efficient cross-effect dynamic nuclear polarization

David Lyndon Emsley, Aaron James Rossini, Dominik Józef Kubicki

A series of 37 dinitroxide biradicals have been prepared and their performance studied as polarizing agents in cross-effect DNP NMR experiments at 9.4 T and 100 K in 1,1,2,2-tetrachloroethane (TCE). We observe that in this regime the DNP performance is str ...

Royal Soc Chemistry2016

Method for the generation of radicals for dynamic nuclear polarization and uses thereof for nmr, mrs and mri

Christophe Roussel, Arnaud Comment, Tim Rolf Eichhorn

A method for the preparation of a sample comprising highly polarized nuclear spins is proposed, comprising at least the following steps: a) provision of molecules with 1,2-dione structural units and/or molecules with 2,5-diene-1,4-dione structural units in ...

2016

Kinetic isotope effects for fast deuterium and proton exchange rates

Geoffrey Bodenhausen, Daniele Mammoli, Estel Canet Martinez, Pavel Kaderavek

By monitoring the effect of deuterium decoupling on the decay of transverse N-15 magnetization in D-N-15 spin pairs during multiple-refocusing echo sequences, we have determined fast D-D exchange rates k(D) and compared them with fast H-H exchange rates k( ...

Royal Society of Chemistry2016