Publication
Long-term effects of early treatment with SSRIs on cognition and brain development in individuals with 22q11.2 deletion syndrome
Publications associées (76)
Exploring associations between diurnal cortisol, stress, coping and psychopathology in adolescents and young adults with 22q11.2 deletion syndrome
Maria del Carmen Sandi Perez, Olivia Zanoletti, Maude Schneider, Farnaz Delavari
Background: 22q11.2 deletion syndrome (22q11DS) is a neurogenetic condition associated to a high risk for psychiatric disorders, including psychosis. Individuals with 22q11DS are thought to experience increased levels of chronic stress, which could lead to ...
2022Neuroscience robotics for controlled induction and real-time assessment of hallucinations
Olaf Blanke, Fosco Bernasconi, Jevita Potheegadoo, Herberto Dhanis Pedro De Barros Camacho, Giulio Rognini, Masayuki Hara, Eva Blondiaux, Laurent Frédéric Jenni
Although hallucinations are important and frequent symptoms in major psychiatric and neurological diseases, little is known about their brain mechanisms. Hallucinations are unpredictable and private experiences, making their investigation, quantification a ...
2022New Insights Into the Pivotal Role of CREB-Regulated Transcription Coactivator 1 in Depression and Comorbid Obesity
Antoine Timothée Cherix, Jean-René Cardinaux
Depression and obesity are major public health concerns, and there is mounting evidence that they share etiopathophysiological mechanisms. The neurobiological pathways involved in both mood and energy balance regulation are complex, multifactorial and stil ...
FRONTIERS MEDIA SA2022Agency Deficits in a Human Genetic Model of Schizophrenia: Insights From 22q11DS Patients
Olaf Blanke, Maude Schneider, Nathan Quentin Faivre, Roy Salomon, Oliver Alan Kannape, Mariia Kaliuzhna, Henrique Galvan Debarba
Schizophrenia is a chronic and disabling mental illness characterized by a disordered sense of self. Current theories suggest that deficiencies in the sense of control over one’s actions (Sense of Agency, SoA) may underlie some of the symptoms of schizophr ...
2022The critical periods of cerebral plasticity: A key aspect in a dialog between psychoanalysis and neuroscience centered on the psychopathology of schizophrenia
Through research into the molecular and cellular mechanisms that occur during critical periods, recent experimental neurobiological data have brought to light the importance of early childhood. These have demonstrated that childhood and early environmental ...
FRONTIERS MEDIA SA2022Altered developmental trajectories of verbal learning skills in 22q11.2DS: associations with hippocampal development and psychosis
Maude Schneider, Karin Bortolin
Background The cognitive profile in 22q11.2 deletion syndrome (22q11.2DS) is often characterized by a discrepancy between nonverbal vs. verbal reasoning skills, in favor of the latter skills. This dissociation has also been observed in memory, with verbal ...
CAMBRIDGE UNIV PRESS2022The shine-through paradigm and the schizophrenia spectrum: a summary
Michael Herzog, Simona Adele Garobbio, Maya Roinishvili, Ophélie Gladys Favrod
In the past 10 years, our laboratory has proved the shine-through paradigm to be a very sensitive endophenotype for schizophrenia. The shine-through paradigm is a visual backward masking task, where the target is a vertical vernier followed by a 25-element ...
2021Fronto-Temporal Disconnection Within the Presence Hallucination Network in Psychotic Patients With Passivity Experiences
Olaf Blanke, Alessandra Griffa, Jevita Potheegadoo, Patric Hagmann, Kim Do, Nathan Quentin Faivre, Roy Salomon, Giulio Rognini, Eva Blondiaux, Giedre Stripeikyte, Pierre Progin
Psychosis, characterized by hallucinations and delusions, is a common feature of psychiatric disease, especially schizophrenia. One prominent theory posits that psychosis is driven by abnormal sensorimotor predictions leading to the misattribution of self- ...
2021Brain connectivity and metacognition in persons with subjective cognitive decline (COSCODE): rationale and study design
Background Subjective cognitive decline (SCD) is the subjective perception of a decline in memory and/or other cognitive functions in the absence of objective evidence. Some SCD individuals however may suffer from very early stages of neurodegenerative dis ...
2021Dysmaturation Observed as Altered Hippocampal Functional Connectivity at Rest Is Associated With the Emergence of Positive Psychotic Symptoms in Patients With 22q11 Deletion Syndrome
Dimitri Nestor Alice Van De Ville, Maude Schneider, Farnaz Delavari, Daniela Maria Zöller, Karin Bortolin
BACKGROUND: Hippocampal alterations are among the most replicated neuroimaging findings across the psychosis spectrum. Moreover, there is strong translational evidence that preserving the maturation of hippocampal networks in mice models prevents the progr ...
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