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Engram cell connectivity: an evolving substrate for information storage

Publications associées (67)

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The HDAC inhibitor CI-994 acts as a molecular memory aid by facilitating synaptic and intracellular communication after learning

Johannes Gräff, Allison Marie Burns, Jose Vicente Sanchez Mut, Giulia Santoni

Long-term memory formation relies on synaptic plasticity, neuronal activity-dependent gene transcription, and epigenetic modifications. Multiple studies have shown that HDAC inhibitor (HDACi) treatments can enhance individual aspects of these processes and ...

2022

Behavioral diversity seen in biological systems is, at the most basic level, driven by interactions between physical materials and their environment. In this context we are interested in falling paper systems, specifically the V-shaped falling paper (VSFP) ...

MIT PRESS2022

In his seminal work, Halbwachs (1950: 132–139) already noted a homology between the resistance of stone and the resistance of cities’ inhabitants to being displaced or effaced. This contribution seeks to study the relationship between the built environment ...

2022

Investigation of Contact Clusters Between Rough Surfaces

Jean-François Molinari, Shijun Yin, Gianluca Costagliola

We investigate the persistence of micro-contacts between two elastic random rough surfaces by means of a simple model for quasi-static sliding. Contact clusters are calculated with the Boundary Element Method, then surfaces are repeatedly displaced to stud ...

SPRINGER/PLENUM PUBLISHERS2022

In the present work, we approach two key aspects of memory formation: associative memory and synaptic consolidation. The storage of associative memory is commonly related to the medial temporal lobe in humans. Experimental evidence shows that the memories ...

EPFL2021

The study investigates how transcranial direct current stimulation (tDCS) over the auditory cortex (AC) modulates memory for melodies under different noise conditions, whilst also considering cumulative disruptive interference effects. Forty-one participan ...

ACADEMIC PRESS INC ELSEVIER SCIENCE2021

Deceased public figures are often said to live on in collective memory. We quantify this phenomenon by tracking mentions of 2,362 public figures in English-language online news and social media (Twitter) 1 y before and after death. We measure the sharp spi ...

NATL ACAD SCIENCES2021

Reenactment and Intangible Heritage Strategies for Embodiment and Transmission in Museums

Sarah Irene Brutton Kenderdine

This article is focused on the interplay of different forms of intangibility (living heritage and reenactment heritage) and the way technologically enabled practices might reshape the role and transformation of intangible cultural heritage (ICH) in museums ...

CENTRUM STUDIE DOCUMENTATIE2020

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The stress response facilitates survival through adaptation and is intimately related to cognitive processes. The Morris water maze task probes spatial learning and memory in rodents and glucocorticoids (i.e. corticosterone (CORT) in rats) have been sugges ...

2019

Stability of working memory in continuous attractor networks under the control of short-term plasticity

Wulfram Gerstner, Alexander Kevin Seeholzer, Moritz Deger

Continuous attractor models of working-memory store continuous-valued information in continuous state-spaces, but are sensitive to noise processes that degrade memory retention. Short-term synaptic plasticity of recurrent synapses has previously been shown ...

PUBLIC LIBRARY SCIENCE2019