Personalizable computational models of electrical spinal cord stimulation to restore function after neurological disorders
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This manuscript reports the effects of transcranial DC stimulation (tDCS), a technique that enhances cortical plasticity in healthy humans, on motor function in a patient with chronic subcortical ischemic stroke. tDCS but not sham applied in a double-blind ...
Introduction:Gait and posture in PD patients are generally analyzed in laboratory. However, laboratory techniques do not allow estimating long-term ON/OFF fluctuation in PD patients. Here, we propose an ambulatory system based on kinematic sensors that det ...
This paper presents the TENECI (Collaborative tele- neurology) project which allows practitioners to use telecommunication technologies to provide medical information and services for neurological diseases. Specificities of remote neurology are described a ...
Parkinson's disease (PD) is a neurologic disorder resulting from the loss of dopaminergic neurons in the brain. Two lines of evidence suggest that the protein alpha-synuclein plays a role in the pathogenesis of PD: Fibrillar alpha-synuclein is a major comp ...
The physical activity in normal daily life is determined to a large extent by the functional ability of a subject. As a result, the measurement of the physical activity that a subject performs spontaneously could be a useful and objective measurement of di ...
Background Physical and functional losses due to aging and diseases decrease human mobility, independence, and quality of life. This study is aimed at summarizing and quantifying these losses in order to motivate solutions to overcome them with a special f ...
Spinal cord stimulation (i.e. the electrical stimulation of the dorsal columns of the spinal cord) isincreasingly used for the treatment of intractable pain syndromes due to vascular or neurogenicdisorders. Despite well-established safety and efficacy in p ...