Large-scale functional network dynamics in human callosal agenesis: Increased subcortical involvement and preserved laterality
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Objective: A study was undertaken to investigate the effect of neonatal hypoxic-ischemic (HI) brain damage and mesenchymal stem cell (MSC) treatment on the structure and contralesional connectivity of motor function-related cerebral areas. Methods: Brain r ...
The amygdalae are involved in the perception of emotions such as happiness, anger and fear. Because of their proximity to the sinuses, the image signal intensity in T2* weighted fMRI data is often affected by signal loss due to through-slice dephasing, esp ...
The corpus callosum (CC) provides the main route of communication between the 2 hemispheres of the brain. In monkeys, chimpanzees, and humans, callosal axons of distinct size interconnect functionally different cortical areas. Thinner axons in the genu and ...
Brain imaging has shown altered corpus callosum (CC) morphology in patients with Gilles de la Tourette syndrome (GTS). Yet it is unclear whether these morphological changes are associated with altered interhemispheric interactions. Here, we combined transc ...
The development of the human brain, from the fetal period until childhood, happens in a series of inter- twined neurogenetical and histogenetical events that are influenced by environment. Neuronal proliferation and mi- gration, cell aggregation, axonal in ...
Magnetic resonance imaging (MRI) is increasingly being used in medical settings because of its ability to produce, non-invasively, high quality images of the inside of the human body. Since its introduction in early 70’s, more and more complex acquisition ...
How the brain integrates signals from specific areas has been a longstanding critical question for neurobiologists. Two recent observations suggest a new approach to fMRI data analysis of this question. First, in many instances, the brain analyzes inputs b ...
Imitation is a fundamental mechanism by which humans learn and understand the actions of others. This thesis addresses the low-level neural mechanisms underlying the imitation of meaningless gestures, using tools from computational neuroscience. We investi ...
Deep brain stimulation (DBS) for Parkinson's disease often alleviates the motor symptoms, but causes cognitive and emotional side effects in a substantial number of cases. Identification of the motor part of the subthalamic nucleus (STN) as part of the pre ...
Papez circuit is one of the major pathways of the limbic system, and it is involved in the control of memory and emotion. Structural and functional alterations have been reported in psychiatric, neurodegenerative, and epileptic diseases. Despite the clinic ...