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Wireless soft microscale actuators and robotic devices to study mechanobiology

Publications associées (59)

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Interaction of glia with a compliant, microstructured silicone surface

Stéphanie Lacour, Ivan Rusev Minev

Soft bioengineered surfaces offer a route towards modulating the tissue responses to chronically implanted devices and may enhance their functionality. In this communication we fabricate microtopographically rich and mechanically compliant silicone surface ...

Elsevier2013

Cell specific ingrowth hydrogels

Matthias Lütolf

Extracellular mimetic hydrogels formed from peptide crosslinkers and polyethylene glycol monomers permit cell-controlled invasion. The use of matrix metalloproteinase specific peptides might further allow for selective control of different cell-type invasi ...

Elsevier Sci Ltd2013

Toxicity study of nanostructures

Lenke Horváth

The great achievement of nanotechnology is the controlled synthesis of a large variety of nanometer-size materials like needle-formed nanotubes, nanowires and two-dimensional graphene flakes. Due to their unique physico-chemical properties, these nanostruc ...

EPFL2012

Photopatterning of Synthetic Hydrogels

Katarzyna Mosiewicz

In recent years sophisticated biomaterials have made a significant impact on our understanding of cellular behavior, particularly in the fields of stem cell research and tissue engineering. Nevertheless, the promising potential of stem cells for regenerati ...

EPFL2012

Differential peptide binding to CD40 evokes counteractive responses

Giovanni Dietler, Sandor Kasas, Charles Roduit, Livan Bladimir Alonso Sarduy, Bhaskar Saha

The antigen-presenting cell-expressed CD40 is implied in the regulation of counteractive immune responses such as induction of pro-inflammatory and anti-inflammatory cytokines interleukin (IL)-12 and IL-10, respectively. The mechanism of this duality in CD ...

Elsevier2012

Biologicals and fetal cell therapy for wound healing and scar management

Dominique Pioletti, Corinne Scaletta, Nathalie Hirt-Burri, Lee Ann Laurent-Applegate

Few biopharmaceutical preparations developed from biologicals are available for tissue regeneration and scar management. When developing biological treatments with cellular therapy, selection of cell types and establishment of consistent cell banks are cru ...

2011

Effect of fluid flow shear stress on Mesenchymal Stem Cells(MSC) differentiation using a microfluidic device

Sohrab Emami Naeini

Mesenchymal Stem Cells (MSC) are multipotent stem cells that are predominantly obtained from the bone marrow. These cells have a high ability to differentiate into a multitude of cell types, which are very attractive for tissue engineering and cell therapy ...

2011

Biomimetic materials in tissue engineering

Jeffrey Alan Hubbell, Mikaël Martino, Jennifer Patterson

Biomaterial matrices are being developed that mimic the key characteristics of the extracellular matrix, including presenting adhesion sites and displaying growth factors in the context of a viscoelastic hydrogel. This review focuses on two classes of mate ...

Elsevier2010

Stem cell-based cardiovascular tissue engineering

Thomas Krähenbühl

Cardiovascular diseases, including myocardial infarction, are the leading cause of death worldwide for both men and women. Current therapies are limited by the restricted intrinsic regeneration capacity of the heart and by the lack of organs for transplant ...

EPFL2009

Tissue engineering of the bladder

Catharina Adelöw

Stem cell use in bladder tissue engineering is a recently addressed area of investigation that has generated excitement as a novel way to restore and regenerate lost or damaged urinary bladder tissue. The remodelling of smooth muscle plays a significant ro ...

EPFL2009