Rhesus Blood Typing within a Few Seconds by Packing-Enhanced Nanoscattering on Individual Erythrocytes
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Obtaining high resolution 3D quantitative images is critical for elucidating the relationship between cell dynamics and physiological or pathological processes. However the feasibility of such cellular dynamic studies is limited by the resolution of the 3D ...
Background and Objectives Microparticles (MPs) are small phospholipid vesicles of less than 1 mu m, shed in blood flow by various cell types. These MPs are involved in several biological processes and diseases. MPs have also been detected in blood products ...
Red blood cell (RBC) parameters such as morphology, volume, refractive index, and hemoglobin content are of great importance for diagnostic purposes. Existing approaches require complicated calibration procedures and robust cell perturbation. As a result, ...
Affinity precipitation was compared to affinity chromatography and batch adsorption as the final purification step in a protocol for the isolation of haemoglobin from human blood. Haptoglobin was the affinity ligand. The first steps on the process were rea ...
Product isolation increasingly becomes a major bottleneck in molecular biotechnology. This is especially the case for the sensitive proteineous substances (recombinant proteins, antibodies) and lately also DNA, usually produced in low concentration. The cu ...
The main purpose of this thesis is to explore a new concept of SNOM probes. In order to produce more reliable and reproducible tips, we propose to graft a single gold particle of 60 nm diameter onto the aperture of a SNOM probe. The expected advantage of s ...
A family of graft copolymers that can sterically inhibit interactions between biological surfaces was developed. These copolymers contained phenylboronic acid (PBA) groups as saccharide-binding moieties on a poly-(L-lysine) backbone and poly(ethylene glyco ...
Replacement of the hyperimmune anti-Rhesus (Rh) D immunoglobulin, currently used to prevent haemolytic disease of the newborn, by fully recombinant human anti-RhD antibodies would solve the current logistic problems associated with supply and demand. The c ...
There are many elements in plasma that can act as surrogate markers of the physiological well-being of a mouse, thus making the collection of blood and plasma a general technique with many applications in mouse phenotyping. For example, the presence of cer ...
A review is given with 2 refs. Hemolytic disease of the newborn is an often fatal condition of some newborn babies due to the immunogenicity of their Rh D pos. erythrocytes in the Rh D neg. mother. This condition can be prevented by injecting anti-Rh D ant ...