Publication
Functional and structural characterization of Serratia marcescens ExbB: determinants of the interaction with HasB/TonB
Publications associées (72)
Microbiological contamination of cosmetic products - observations from Europe, 2005-2018
Florentino Luciano Caetano Dos Santos
Background Although cosmetic products are not expected to be fully aseptic, their potential microbiological contamination might be dangerous, especially for immunocompromised patients. The extent of such contamination of cosmetics in Europe is poorly studi ...
2019Protocols for Subtomogram Averaging of Membrane Proteins in the Dynamo Software Package
Cryo-electron tomography allows low-resolution three-dimensional (3D) viewing of cellular organelles and macromolecular complexes present as multiple copies within a tomogram. These structures are computationally extracted and averaged in order to obtain h ...
Frontiers Media SA2018Inner-membrane GspF of the bacterial type II secretion system is a dimeric adaptor mediating pseudopilus biogenesis
The type II secretion system (T2SS), a protein complex spanning the bacterial envelope, is pivotal to bacterial pathogenicity. Central to T2SS function is the extrusion of protein cargos from the periplasm into the extracellular environment mediated by a p ...
2018FIBCD1 Binds Aspergillus fumigatus and Regulates Lung Epithelial Response to Cell Wall Components
Aspergillus fumigatus (A. fumigatus) is a ubiquitous fungus of clinical importance associated with development of various pulmonary diseases and allergic hypersensitivity reactions. It is protected against environmental stress by a cell wall that contains ...
FRONTIERS MEDIA SA2018Proteoliposomes - a system to study membrane proteins under buffer gradients by cryo-EM
Membrane proteins are vital to life and major therapeutic targets. Yet, understanding how they function is limited by a lack of structural information. In biological cells, membrane proteins reside in lipidic membranes and typically experience different bu ...
Walter de Gruyter GmbH2017Visualizing chemical transport from extracellular symbionts into squid host tissues using NanoSIMS
Chemical communication is the basis of host-microbe interaction. Insights into this communication will provide a deeper understanding of the mechanisms that govern these complex associations, in beneficial as well as pathogenic contexts. In this dissertati ...
EPFL2017Single Cell Electrochemiluminescence Imaging: From the Proof-of-Concept to Disposable Device-Based Analysis
Andreas Stephan Lesch, Milica Jovic
We report here the development of coreactant-based electro-generated chemiluminescence (ECL) as a surface-confined microscopy to image single cells and their membrane proteins. Labeling the entire cell membrane allows one to demonstrate that, by contrast w ...
American Chemical Society2017Bactericidal activity and mechanism of action of copper-sputtered flexible surfaces against multidrug-resistant pathogens
César Pulgarin, Juan Kiwi, Sami Rtimi, Myriam Koumba Sarah Ballo
Using direct current magnetron sputtering (DCMS), we generated flexible copper polyester surfaces (Cu-PES) and investigated their antimicrobial activity against a range of multidrug-resistant (MDR) pathogens including eight Gram-positive isolates (three me ...
Springer Verlag2016The DNA-Uptake Process of Naturally Competent Vibrio cholerae
Melanie Blokesch, Noémie Matthey
The sophisticated DNA-uptake machinery used during natural transformation is still poorly characterized, especially in Gram-negative bacteria where the transforming DNA has to cross two membranes as well as the peptidoglycan layer before entering into the ...
Elsevier2016Chemometric Analysis of Bacterial Peptidoglycan Reveals Atypical Modifications That Empower the Cell Wall against Predatory Enzymes and Fly Innate Immunity
Peptidoglycan is a fundamental structure for most bacteria. It contributes to the cell morphology and provides cell wall integrity against environmental insults. While several studies have reported a significant degree of variability in the chemical compos ...
American Chemical Society2016