Novel High-Throughput Fluorescence-Based Assay for the Identification of Nematocidal Compounds That Target the Blood-Feeding Pathway
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A review. With the advances in genomics, proteomics and functional genomics new therapeutic targets to be tackled by medicinal chem. are expected. This article reviews applications of first principle methods to address medicinal chem. issue related to drug ...
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This article reports the design, synthesis and results of first in vitro model studies of a conceptually novel class of polymer therapeutics in which the cargo is attached to a polymer backbone via a noncovalent, biologically inspired coiled coil linker, w ...
We present a novel OptoMEA platform that combines multisite electrical recording with local chemical stimulation. Applying UV light pulses through an array of optical fibres aligned to transparent indium-tin oxide electrodes of an MEA biochip leads to loca ...
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Because vascular occlusion has been observed as a consequence of photodynamic therapy (PDT), this method has been successfully used for the treatment of choroidal neovascularization (CNV) in age-related macular degeneration (AMD). However, most conventiona ...
