Deconstructing body axis morphogenesis in zebrafish embryos using robot-assisted tissue micromanipulation
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A single intra-peritoneal injection of valproic acid (VPA) on embryonic day (ED) 11.5 to pregnant rats has been shown to produce severe autistic-like symptoms in the offspring. Previous studies showed that the microcircuitry is hyperreactive due to hyperco ...
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Vertebrate somitogenesis is a rhythmically repeated morphogenetic process. The dependence of somitogenesis dynamics on axial position and temperature has not been investigated systematically in any species. Here we use multiple embryo time-lapse imaging to ...
In a simultaneous experiment we studied the de Haas–van Alphen (dHvA) and the Shubnikov–de Haas (SdH) effects in a two-dimensional electron system (2DES) in a modulation-doped GaAs∕AlxGa1−xAs heterostructure. For this, a gated 2DES mesa was monolithically ...
In this issue of Developmental Cell, Sakano et al. describe a novel mechanism of how a key lymphocyte transcription factor crosstalks to Notch signaling during embryonic development and thereby selectively inhibits Notch-activated target genes to allow pro ...
