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V-ATPase/TORC1-mediated ATFS-1 translation directs mitochondrial UPR activation in C. elegans

Publications associées (35)

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Drug Screening in C. elegans to identify new pharmacological mitochondrial stress inducers

Amélia Lalou

Mitochondria are essential organelles participating in numerous cellular functions, including energy harvesting, regulation of homeostasis and apoptosis. Changes in mitochondrial number, morphology, and function not only impact cellular metabolism but also ...

EPFL2024

Biochemistry of Aminoacyl tRNA Synthetase and tRNAs and Their Engineering for Cell-Free and Synthetic Cell Applications

Sebastian Maerkl, Ragunathan Bava Ganesh

Cell-free biology is increasingly utilized for engineering biological systems, incorporating novel functionality, and circumventing many of the complications associated with cells. The central dogma describes the information flow in biology consisting of t ...

FRONTIERS MEDIA SA2022

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The present invention relates to systems and methods for planning and/or providing neuromodulation One example system includesa stimulation related basic data storage module for storing stimulation related basic data,a stimulation related response data sto ...

2021

Discourse Phenomena in Machine Translation

Lesly Sadiht Miculicich Werlen

Machine Translation (MT) has made considerable progress in the past two decades, particularly after the introduction of neural network models (NMT). During this time, the research community has mostly focused on modeling and evaluating MT systems at the se ...

EPFL2021

Disruption of mitochondrial redox homeostasis by enzymatic activation of a trialkylphosphine probe

Pablo Rivera Fuentes, Jade Noémie Nam Nguyen

Redox homeostasis is essential for cell function and its disruption is associated with multiple pathologies. Redox balance is largely regulated by the relative concentrations of reduced and oxidized glutathione. In eukaryotic cells, this ratio is different ...

ROYAL SOC CHEMISTRY2021

This conversation focuses on the work of Sarah Kenderdine and Merete Sanderhoff, both of whom are based in Europe working on and within museums, as well as playing leadership roles in pan-institutional organisations such as Europeana and the Australasian A ...

Routledge2020

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Oscillator system (1) comprising:- a substantially planar frame (3);- a first sub-oscillator (5), a second sub-oscillator (7), a third sub-oscillator (9), and a fourth sub-oscillator (11), each sub-oscillator (5, 7, 9, 11) comprising a substantially rigid ...

2020

A system for planning and/or providing neuromodulation

Grégoire Courtine, Vincent Delattre, Marco Capogrosso, Fabien Bertrand Paul Wagner, Karen Minassian

The present invention relates to a system for planning and/or providing neuromodulation (10), especially neurostimulation, comprising: - first data input module (26) for stimulation related basic data, - a stimulation related basic data storage module (28) ...

2019

Word Sense Consistency in Statistical and Neural Machine Translation

Xiao Pu

Different senses of source words must often be rendered by different words in the target language when performing machine translation (MT). Selecting the correct translation of polysemous words can be done based on the contexts of use. However, state-of-th ...

EPFL2018

The design process is a series of endeavors aimed to solve a problem, which is extensively defined as a need, a task, a situation, etc. Visualizations are objects that result from a design process that solves a problem of unreadable data. They are technica ...

2018