AI-Based Estimation of End-Systolic Elastance From Arm-Pressure and Systolic Time Intervals

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Hypertension is the most common cause of left ventricular hypertrophy, contributing to heart failure progression. Candesartan (Cand) is an angiotensin receptor antagonist widely used for hypertension treatment. Structural modifications were previously perf ...

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The aim of this paper is to introduce a new mathematical model that simulates myocardial blood perfusion that accounts for multiscale and multiphysics features. Our model incorporates cardiac electrophysiology, active and passive mechanics, hemodynamics, v ...

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On the similarity between aortic and carotid pressure diastolic decay: a mathematical modelling study

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Aortic diastolic pressure decay (DPD) has been shown to have considerable pathophysiological relevance in the assessment of vascular health, as it is significantly affected by arterial stiffening. Nonetheless, the aortic pressure waveform is rarely availab ...

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Cardiac output estimated from an uncalibrated radial blood pressure waveform: validation in an in-silico-generated population

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Many research questions concern treatment effects on outcomes that can recur several times in the same individual. For example, medical researchers are interested in treatment effects on hospitalizations in heart failure patients and sports injuries in ath ...

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Data-driven approaches for non-invasive cuffless blood pressure monitoring

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Blood pressure (BP) is a crucial indicator of cardiovascular health. Hypertension is a common life-threatening condition and a key factor of cardiovascular diseases (CVDs). Identifying abnormal BP fluctuations can allow for early detection and management o ...

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The integration of technology in the medical field has greatly improved accuracy in diagnoses, thus leading to more effective treatments. Wearable and implantable medical devices offer great potential for remote patient monitoring, particularly for heart f ...

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Design and computational optimization of compliance-matching aortic grafts

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Introduction: Synthetic vascular grafts have been widely used in clinical practice for aortic replacement surgery. Despite their high rates of surgical success, they remain significantly less compliant than the native aorta, resulting in a phenomenon calle ...

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We propose a mathematical and numerical model for the simulation of the heart function that couples cardiac electrophysiology, active and passive mechanics and hemodynamics, and includes reduced models for cardiac valves and the circulatory system. Our mod ...

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Cardiac output estimated from an uncalibrated radial blood pressure waveform: validation in an in-silico-generated population

Nikolaos Stergiopoulos, Georgios Rovas, Vasiliki Bikia

FRONTIERS MEDIA SA2023

A mathematical model that integrates cardiac electrophysiology, mechanics, and fluid dynamics: Application to the human left heart

Alfio Quarteroni, Luca Dede'

Wiley2023