MnO2 nanosheets as an artificial enzyme to mimic oxidase for rapid and sensitive detection of glutathione

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A new target for gold(I) compounds: glutathione-S.transferase inhibition by auranofin

Paul Joseph Dyson, Christian Hartinger, Angela Casini

Nowadays, gold compounds occupy a relevant position constituting a promising class of experimental anticancer metallodrugs. Several research efforts have been devoted to the investigations of the pharmacological properties of gold(I) complexes bearing phos ...

Elsevier Science Inc2013

A constrained-optimization methodology for the detection phase in contact mechanics simulations

Jean-François Molinari, Vladislav Yastrebov, Alejandro Marcos Aragon

The detection phase in computational contact mechanics can be subdivided into a global search and a local detection. When potential contact is detected by the former, a rigorous local detection determines which surface elements come or may come in contact ...

Wiley2013

Study of Topoisomerase-DNA Interaction Using Atomic Force Microscopy

Livan Bladimir Alonso Sarduy

The aim of this thesis was to explore the topoisomerase-DNA interactions using atomic force microscopy (AFM) in a liquid environment. Firstly, we present a programmable microcontroller-driven injection system for the exchange of an imaging medium while usi ...

EPFL2012

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