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An active strain formulation for orthotropic constitutive laws arising in cardiac mechanics modeling is introduced and studied. The passive mechanical properties of the tissue are described by the Holzapfel-Ogden relation. In the active strain formulation, ...
In this paper we present a compact review on the mostly used techniques for computational reduction in numerical approximation of partial differential equations. We highlight the common features of these techniques and provide a detailed presentation of th ...
Background: In this paper, we present a framework for improving the accuracy of fixed-step methods for Monte Carlo simulation of discrete stochastic chemical kinetics. Stochasticity is ubiquitous in many areas of cell biology, for example in gene regulatio ...
A stabilized semidiscrete finite element discretization of the transient transport equation is studied in the framework of anisotropic meshes. A priori and a posteriori error estimates are derived, the involved constants being independent of the mesh aspec ...
This monograph addresses the state of the art of reduced order methods for modeling and computational reduction of complex parametrized systems, governed by ordinary and/or partial differential equations, with a special emphasis on real time computing tech ...
We consider goal-oriented a posteriori error estimators for the evaluation of the errors on quantities of interest associated with the solution of geometrically nonlinear curved elastic rods. For the numerical solution of these nonlinear one-dimensional pr ...
The subject of this workshop was numerical methods that preserve geometric properties of the flow of an ordinary or partial differential equation. This was complemented by the question as to how structure preservation affects the long-time behaviour of num ...
The objective of this thesis is to develop reduced models for the numerical solution of optimal control, shape optimization and inverse problems. In all these cases suitable functionals of state variables have to be minimized. State variables are solutions ...
Engineers rely on efficient simulations that provide them with reliable data in order to make proper engineering design decisions. The purpose of this thesis is to design adaptive numerical methods for multiscale problems in this spirit. We consider ellipt ...
The aim of this work is the development of a geometrical multiscale framework for the simulation of the human cardiovascular system under either physiological or pathological conditions. More precisely, we devise numerical algorithms for the partitioned so ...