Mimicking Loading-Induced Cartilage Self-Heating in Vitro Promotes Matrix Formation in Chondrocyte-Laden Constructs with Different Mechanical Properties
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Articular cartilage regeneration poses particularly tough challenges for implementing cell-based therapies. Many cell types have been investigated looking for a balanced combination of responsiveness and stability, yet techniques are still far from definin ...
Cartilage tissue engineering aims to develop a material that can be implanted with cells to repair damage in articular cartilage. The extracellular matrix is known to play a key role in regulating stem cell behaviour via cell-matrix interactions and integr ...
Articular cartilage plays important roles in weight-bearing, lubrication, and load distribution in articulating joints. The tissue is mostly extracellular matrix (>90% by volume) that is synthesized and remodeled by cells (chondrocytes) embedded within. Ad ...
Dynamic Mechanical Analysis was conducted on a polyurethane adhesive at different constant heating rates up to 100°C, covering the glass transition range. Different storage modulus degradation curves were obtained from different heating rates. The differen ...
The extracellular matrix of dense, avascular tissues presents a barrier to entry for polymer-based therapeutics, such as drugs encapsulated within polymeric particles. Here, we present an approach by which polymer nanoparticles, suffciently small to enter ...
Temperature dependence of physical and mechanical properties is considered in most thermal and mechanical response models for composite materials. Based on thermogravimetry analysis, differential scanning calorimetry, and dynamic mechanical analysis conduc ...
Nowadays, cartilage repair is a worldwide centre of interest due to the low potential of cartilage to heal spontaneously and the increasing number of patients around the world. One of the techniques to treat cartilage defect is to use autologous human seru ...
Osteoarthritis (OA) is one of the most common causes of pain and disability. Currently, non-surgical treatment is limited to analgesic and anti-inflammatory drugs, which are not capable of either modifying the disease process or regenerate damaged parts in ...
A decomposition model for resin in glass fiber-reinforced polymer composites (GFRP) under elevated and high temperature was derived from chemical kinetics. Kinetic parameters were determined by four different methods using thermal gravimetric data at diffe ...
In the framework of spine traumatology, burst fractures are severe and are often caused by car accidents or by falls. The vertebra breaks under the traumatic compression and pieces of it are shattered in all directions. This type of fracture is often treat ...
