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Caspase-9-mediated cleavage of vimentin attenuates the aggressiveness of leukemic NB4 cells
Publications associées (43)
Ru(II)-Arene Complexes of Curcumin and Bisdesmethoxycurcumin Metabolites
Paul Joseph Dyson, Farzaneh Fadaei Tirani, Mouna Hadiji
Curcuminoids and their complexes continue to attract attention in medicinal chemistry, but little attention has been given to their metabolic derivatives. Here, the first examples of (arene)Ru(II) complexes with curcuminoid metabolites, tetrahydrocurcumin ...
Amer Chemical Soc2024Multitarget-Directed Gallium(III) Tris(acyl-pyrazolonate) Complexes Induce Ferroptosis in Cancer Cells via Dysregulation of Cell Redox Homeostasis and Inhibition of the Mevalonate Pathway
A series of Ga(Q(n))(3) coordination compounds have been synthesized, where HQ(n) is 1-phenyl-3-methyl-4-RC(=O)-pyrazolo-5-one. The complexes have been characterized through analytical data, NMR and IR spectroscopy, ESI mass spectrometry, elemental analysi ...
AMER CHEMICAL SOC2023Colon tumour cell death causes mTOR dependence by paracrine P2X4 stimulation
Solid cancers exhibit a dynamic balance between cell death and proliferation ensuring continuous tumour maintenance and growth(1,2). Increasing evidence links enhanced cancer cell apoptosis to paracrine activation of cells in the tumour microenvironment in ...
NATURE PORTFOLIO2022