A guide to preclinical evaluation of hydrogel-based devices for treatment of cartilage lesions
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In this study we present a photocrosslinkable and layerable hydrogel based on decellularized extracellular matrix (dECM) intended for in vitromodels of cartilage tissue formation. dECM can provide cellular environments that are close to the native tissue s ...
Articular cartilage, together with skin, was predicted to be one of the first tissues to be successfully engineered. However cartilage repair remains nowadays still elusive, as we are still not able to overcome the hurdles of creating biomaterials correspo ...
Classical peer review has been subject to intense criticism for slowing down the publication process, bias against specific categories of paper and author, unreliability, inability to detect errors and fraud, unethical practices, and the lack of recognitio ...
The terrorist attacks of September 11, 2001 raised major concerns about the vulnerability of global transportation systems to transnational crime and terrorism. Although the attacks occurred in the context of passenger transport, they spurred unprecedented ...
Accessing 3R information for fundamental research is difficult for many reasons: the titles, abstracts, and author keywords of scientific articles do not contain the terms 3R, Reduce, Refine, Replace, alternatives or replacement. Mesh terms in Pubmed or th ...
A paradigm shift is taking place in medicine and dentistry from using synthetic implants and tissue grafts to a tissue engineering approach that uses degradable porous three-dimensional (3D) material hydrogels integrated with cells and bioactive factors to ...
Falls are by far the leading cause of fractures and accidents in the home environment. The current Cochrane reviews and other systematic reviews report on more than 200 intervention studies about fall prevention. A recent meta-analysis has summarized the m ...
Photopolymerization is a common tool to harden materials initially in a liquid state. A surgeon can directly trigger the solidification of a dental implant or a bone or tissue filler. Traditionally, photopolymerization has been used mainly in dentistry. Ov ...
Nanoparticles show several interesting new physical and biological properties and therefore play an increasing role in pharmaceutics and medicine. For more than 30 years this research field has been developing slowly but steadily from physical and biologic ...
Swiss Medical Publishers Ltd / EMH Swiss Medical Publishers2010
BACKGROUND:The evolving concepts of pervasive computing, ubiquitous computing and ambient intelligence are increasingly influencing health care and medicine. Summarizing published research, this literature review provides an overview of recent developments ...
