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We attempted ultrasonic welding as a technique for the bonding of connectors to microfluidic devices. Different schemes of the method were explored based on different designs of the connectors to achieve a strong, minimal dead-volume connection. Results sh ...
This paper reports on a new microfluidic chip designed for cell electrofusion. A pair of cells is brought into close contact by means of opposite dielectrophoretic forces and they are subsequently fused by applying a short electrical pulse. ...
[...] Studying axon guidance by diffusible or substrate bound gradients is challenging with current techniques. In this study, we present two microfluidic devices to study axon guidance. [... click on "Download fulltext" for full abstract] ...
A novel UV-curable low-stress hyperbranched polymer (HBP) micromolding process is presented for the fast and low-temperature fabrication of hydrophilic microfluidic devices. Process, material and surface properties of the acrylated polyether HBP are also c ...
The main aim of this project was to develop novel concepts for miniaturization of bioanalytical techniques for investigating biomolecular interactions. We used optical tweezers to selectively address individual biological objects in microfluidic channels. ...
We present a 3-D microfluidic device designed for localized drug delivery to cellular networks. The device features a flow cell comprising a main channel for nutrient delivery as well as multiple channels for drug delivery. This device is one key component ...
This dissertation reports on the development of devices and concepts for electrical and microfluidic cell manipulation. In the present context, the term cell manipulation stands for both cell handling and cell modification. The combination of microfluidic ...
The processing and application of graphite powder-based sacrificial layer for fabrication of microfluidic structures in LTCC is described. Such layers are produced as pastes, which are screen-printed in LTCC sheets to avoid sagging, by supporting closed, t ...
We present a technology for the fabrication of three dimensional microfluidic channels in optically transparent substrates consisting of polymers with different properties. The microstructures are fabricated using polymer replication techniques with a view ...
We form water-in-oil droplets in a microfluidic channel-nozzle geometry for studying the influence of viscosity of oil and of different oil classes on the droplet size. We find that the chemical structure of oil dominates over its viscosity. Our studies ar ...
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