Publication
Molecular reconstruction and simulation of the Neuron-Glia-Vasculature system
Publications associées (156)
Parental status and markers of brain and cellular age: A 3D convolutional network and classification study
Recent research shows prominent effects of pregnancy and the parenthood transition on structural brain characteristics in humans. Here, we present a comprehensive study of how parental status and number of children born/fathered links to markers of brain a ...
Pergamon-Elsevier Science Ltd2024Non-invasive neuromodulation of the right temporoparietal junction using theta-burst stimulation in functional neurological disorder
Background Disrupted sense of agency (SoA)-the sense of being the agent of one's own actions-has been demonstrated in patients with functional neurological disorder (FND), and a key area of the corresponding neuronal network is the right temporoparietal ju ...
London2024Aptamer Renaissance for Neurochemical Biosensing
Unraveling the complexities of brain function, which is crucial for advancing human health, remains a grand challenge. This endeavor demands precise monitoring of small molecules such as neurotransmitters, the chemical messengers in the brain. In this Pers ...
2024Neuroengineering of hallucinations through fMRI neurofeedback: Understanding and modulating neural dynamics for the control of hallucinations in health and disease
Herberto Dhanis Pedro De Barros Camacho
Recent years have seen considerable progress in understanding brain function, and in modulating it through real-time fMRI neurofeedback (NF). Inspired by these advances, paired with the unique possibility of inducing the clinically relevant Presence Halluc ...
EPFL2023Tissue clearing applications in memory engram research
Johannes Gräff, Kwok Yui Reymond Yip
A memory engram is thought to be the physical substrate of the memory trace within the brain, which is generally depicted as a neuronal ensemble activated by learning to fire together during encoding and retrieval. It has been postulated that engram cell e ...
FRONTIERS MEDIA SA2023Brain mitochondrial diversity and network organization predict anxiety-like behavior in male mice
The brain and behavior are under energetic constraints, limited by mitochondrial energy transformation capacity. However, the mitochondria-behavior relationship has not been systematically studied at a brain-wide scale. Here we examined the association bet ...
2023Brain dynamics uncovered using a machine-learning algorithm
CEBRA is a machine-learning method that can be used to compress time series in a way that reveals otherwise hidden structures in the variability of the data. It excels at processing behavioural and neural data recorded simultaneously, and it can decode act ...
NATURE PORTFOLIO2023Automated neuron tracking inside moving and deforming C. elegans using deep learning and targeted augmentation
Sahand Jamal Rahi, Kseniia Korchagina
Reading out neuronal activity from three-dimensional (3D) functional imaging requires segmenting and tracking individual neurons. This is challenging in behaving animals if the brain moves and deforms. The traditional approach is to train a convolutional n ...
Berlin2023Surprise and novelty in the brain
Wulfram Gerstner, Johanni Michael Brea, Alireza Modirshanechi, Sophia Becker
Notions of surprise and novelty have been used in various experimental and theoretical studies across multiple brain areas and species. However, 'surprise' and 'novelty' refer to different quantities in different studies, which raises concerns about whethe ...
CURRENT BIOLOGY LTD2023Revealing the complexity of ultra-soft hydrogel re-swelling inside the brain
Stéphanie Lacour, John Martin Kolinski, Outman Akouissi, Olivier Didier Christian Rizzo, Michael Shur
The brain is an ultra-soft viscoelastic matrix. Sub-kPa hydrogels match the brain's mechanical properties but are challenging to manipulate in an implantable format. We propose a simple fabrication and processing sequence, consisting of de-hydration, patte ...
2023