Molecular reconstruction and simulation of the Neuron-Glia-Vasculature system
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In neuroscience, as in many other scientific domains, the primary form of knowledge dissemination is through published articles. One challenge for modern neuroinformatics is finding methods to make the knowledge from the tremendous backlog of publications ...
The last two decades have seen an unprecedented development of human brain mapping approaches at various spatial and temporal scales. Together, these have provided a large fundus of information on many different aspects of the human brain including micro- ...
The neocortex is one of the most important brain regions, occupying more than 80% of the brain volume in mammals and contributing massively to its capability of perceiving and interpreting then environment. While it has been extensively studied, it is stil ...
The basal forebrain (BF) houses major ascending projections to the entire neocortex that have long been implicated in arousal, learning, and attention. The disruption of the BF has been linked with major neurological disorders, such as coma and Alzheimer's ...
The brain is probably the most complex system of the human body, composed of numerous neural units interconnected at dierent scales. This highly structured architecture provides the ability to communicate, synthesize information and perform the analytical ...
Neurological disorders disrupt the equilibrium within the brain and spinal cord ecosystems. Ecology reuses, recycles, and reduces to help maintain the balance across ecosystems. Likewise, neuroprosthetics can help the brain help itself with ecoprosthetic d ...
Photobiomodulation (PBM) is a promising approach to treat Parkinson's disease (PD) symptoms in cellular or animal models. Unfortunately, little information is available on the optical parameters playing a role in the light dosimetry during PBM. We conducte ...
The research community is witnessing expansive efforts aimed at understanding one of the most wondrous manifestations of cognition in nature. The Blue Brain Project and the Human Brain Project in Europe are examples of ambitious drives aimed at building a ...
Institute of Electrical and Electronics Engineers2014
Cerebral cartography can be understood in a limited, static, neuroanatomical sense. Temporal information from electrical recordings contributes information on regional interactions adding a functional dimension. Selective tagging and imaging of molecules a ...
The goal of the Human Brain Project is to develop, during the next decade, an infrastructure capable of simulating a draft human brain model based on available experimental data. One of the key issues is therefore to integrate and make accessible the exper ...