Publication

Acoustofluidic large-scale mixing for enhanced microfluidic immunostaining for tissue diagnostics

Publications associées (46)

Graph Chatbot

Chattez avec Graph Search

Posez n’importe quelle question sur les cours, conférences, exercices, recherches, actualités, etc. de l’EPFL ou essayez les exemples de questions ci-dessous.

AVERTISSEMENT : Le chatbot Graph n'est pas programmé pour fournir des réponses explicites ou catégoriques à vos questions. Il transforme plutôt vos questions en demandes API qui sont distribuées aux différents services informatiques officiellement administrés par l'EPFL. Son but est uniquement de collecter et de recommander des références pertinentes à des contenus que vous pouvez explorer pour vous aider à répondre à vos questions.

Connectez-vous pour utiliser Chat avec Graph Search

, , , ,

Magnetic micro-and nanoparticles ('magnetic beads') have been used to advantage in many microfluidic devices for sensitive antigen (Ag) detection. Today, assays that use as read-out of the signal the number count of immobilized beads on a surface for quant ...

Elsevier2015

The nanoimmunoassay chip comprises at least flow and control layers, divided into several rows, each row containing a plurality of single assay units, each assay unit contains two spotting chambers (1) and an assay chamber in the middle, wherein neck valve ...

2015

Turbulent-laminar patterns in plane Poiseuille flow

Tobias Schneider, Tobias Klaus Kreilos

Turbulent-laminar banded patterns in plane Poiseuille flow are studied via direct numerical simulations in a tilted and translating computational domain using a parallel version of the pseudospectral code Channelflow. 3D visualizations via the streamwise v ...

Amer Inst Physics2014

Integration of liquid crystals molecules in optofluidic devices

Julien Cuennet

It is in the context of miniaturization that arises the microfluidics concept. It is not uncommon in chemical, biological or medical analysis laboratories to manipulate or to mix fluids while measuring the results with filters, spectrometers or all other e ...

EPFL2014

Pressure lies at the basis of operation of most microfluidic systems, and is a determinant factor in the extent of miniaturization and in limiting the throughput and time constant of the microfluidic assays. Despite the apparent importance given to fluidic ...

EPFL2013

Attomolar protein detection using a magnetic bead surface coverage assay

Martinus Gijs, Matteo Cornaglia, Hüseyin Cumhur Tekin

We demonstrate a microfluidic method for ultra-sensitive protein detection in serum. First, ‘large’ (2.8 μm) antibody-functionalized magnetic beads specifically capture antigen from a serum matrix under active microfluidic mixing. Subsequently, the large b ...

Royal Society of Chemistry2013

High Throughput-Per-Footprint Inertial Focusing

Martinus Gijs, Ata Tuna Ciftlik, Maxime Ettori

Matching the scale of microfluidic flow systems with that of microelectronic chips for realizing monolithically integrated systems still needs to be accomplished. However, this is appealing only if such re-scaling does not compromise the fluidic throughput ...

Wiley-V C H Verlag Gmbh2013

Deformable Droplets, a numerical account

François Gallaire, Mathias Nagel

We simulate confined droplets in microchannels by depth-averaged equations solved by a boundary element method. The retarding effect due to film formation is absent in the depth-averaged approach and added by a nonlinear boundary condition. Although deform ...

2013

Automated Analysis of Rare Biomarkers Using a Magnetic Bead Surface Coverage Assay Coupled with Chaotic Mixing on a Microfluidic Chip

Hüseyin Cumhur Tekin

Extremely sensitive protein detection is crucial for early diagnosis and monitoring of diseases. Present day’s limit of detection for an antibody-antigen recognition-based immunoassay in serum without having to use special target antigen amplification tech ...

EPFL2012

Optofluidic differential spectroscopy for absorbance detection of sub-nanolitre liquid samples

Wuzhou Song, Jianhang Yang

We present a novel optofluidic differential method for carrying out absorbance spectroscopy of subnanolitre volumes of liquid samples on a microfluidic chip. Due to the reduction of liquid volume, the absorbance detection in microfluidics is often hindered ...

Royal Society of Chemistry2012