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Genetic approaches to control DNA expression in different brain areas have provided an excellent system to characterize gene function in health and disease of animal models. With respect to others, in utero electroporation of exogenous DNA into progenitor ...
Exploring the anatomical and functional connectivities between different regions of the brain (the “Connectome”) is a core challenge in neuroscience. While robust methods are available for the adult brain, mapping the connectome in neonates is highly chall ...
The Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative has focused scientific attention on the necessary tools to understand the human brain and mind. Here, we outline our collective vision for what we can achieve within a dec ...
Multisensory experiences influence subsequent memory performance and brain responses. Studies have thus far concentrated on semantically congruent pairings, leaving unresolved the influence of stimulus pairing and memory sub-types. Here, we paired images w ...
Imitation is a fundamental mechanism by which humans learn and understand the actions of others. This thesis addresses the low-level neural mechanisms underlying the imitation of meaningless gestures, using tools from computational neuroscience. We investi ...
From its introduction, in utero electroporation has arisen as a powerful tool to manipulate neural-precursor cells of the parietal cortex and their progeny in vivo. Although this technique has unlimited potentials for targeting numerous brain areas, the ex ...
The understanding of brain function requires the development of new methods to perturb and track distinct neuronal populations in the developing and adult central nervous system. Over the past ten years, in utero electroporation (IUE) has arisen as an extr ...
We review recent rain-scanning (fMRI) evidence that activity in certain sub-cortical structures of the human brain correlate with changes in expected reward, as well as with risk. Risk is measured by variance of payoff, as in Markowitz' theory. The brain s ...
IBM's Blue Gene supercomputer allows a quantum leap in the level of detail at which the brain can be modelled. I argue that the time is right to begin assimilating the wealth of data that has been accumulated over the past century and start building biolog ...
How does the brain build a comprehensible picture of the visible world? Research over recent decades has taught us that the brain does not, in fact, process a given scene as a whole. Instead parts of the brain work independently and in parallel to process ...
