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Aptamer Renaissance for Neurochemical Biosensing

Publications associées (33)

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Task-Driven Activity Reduces the Cortical Activity Space of the Brain: Experiment and Whole-Brain Modeling

Patric Hagmann

How a stimulus or a task alters the spontaneous dynamics of the brain remains a fundamental open question in neuroscience. One of the most robust hallmarks of task/stimulus-driven brain dynamics is the decrease of variability with respect to the spontaneou ...

Public Library Science2015

Multiphoton microscopy in brain imaging

Graham Knott, Bohumil Maco, Ludovico Silvestri

Brain imaging is becoming an important field in the frame of the neurophotonics in correlations with other medical ones in neuroscience studying functional and morphological aspects. In this presentation an overview on multi photon imaging of the brain wil ...

Spie-Int Soc Optical Engineering2015

Dynamic brain networks explored by structure-revealing methods

Nora Leonardi

The human brain is a complex system able to continuously adapt. How and where brain activity is modulated by behavior can be studied with functional magnetic resonance imaging (fMRI), a non-invasive neuroimaging technique with excellent spatial resolution ...

EPFL2014

Ammonia toxicity to the brain

Cristina Ramona Cudalbu

Hyperammonemia can be caused by various acquired or inherited disorders such as urea cycle defects. The brain is much more susceptible to the deleterious effects of ammonium in childhood than in adulthood. Hyperammonemia provokes irreversible damage to the ...

Springer Verlag2013

Multimodal evaluation of the pediatric brain: DTI and its competitors

Elda Fischi Gomez

The development of the human brain, from the fetal period until childhood, happens in a series of intertwined neurogenetical and histogenetical events that are influenced by environment. Neuronal proliferation and migration, cell aggregation, axonal ingrow ...

Springer Verlag2013

Increased performance in genetic manipulation by modeling the dielectric properties of the rodent brain

Diego Ghezzi

Genetic approaches to control DNA expression in different brain areas have provided an excellent system to characterize gene function in health and disease of animal models. With respect to others, in utero electroporation of exogenous DNA into progenitor ...

2013

Altered Synaptic Dynamics during Normal Brain Aging

Graham Knott, Bohumil Maco

What is the neuroanatomical basis for the decline in brain function that occurs during normal aging? Previous postmortem studies have blamed it on a reduction in spine density, though results remain controversial and spine dynamics were not assessed. We us ...

Soc Neuroscience2013

Increased axonal bouton dynamics in the aging mouse cortex

Graham Knott, Bohumil Maco, Ge Gao

Aging is a major risk factor for many neurological diseases and is associated with mild cognitive decline. Previous studies suggest that aging is accompanied by reduced synapse number and synaptic plasticity in specific brain regions. However, most studies ...

National Academy of Sciences2013

High-performance and site-directed in utero electroporation by a triple-electrode probe

Diego Ghezzi

From its introduction, in utero electroporation has arisen as a powerful tool to manipulate neural-precursor cells of the parietal cortex and their progeny in vivo. Although this technique has unlimited potentials for targeting numerous brain areas, the ex ...

2012

Electrical neuroimaging of memory discrimination based on single-trial multisensory learning

Micah Murray, Antonia Thelen

Multisensory experiences influence subsequent memory performance and brain responses. Studies have thus far concentrated on semantically congruent pairings, leaving unresolved the influence of stimulus pairing and memory sub-types. Here, we paired images w ...

Elsevier2012